Solid phase adsorption toxin tracking (SPATT): a new monitoring tool that simulates the biotoxin contamination of filter feeding bivalves

MacKenzie, Lincoln; Beuzenberg, Veronica; Holland, Patrick T.; McNabb, Paul; Selwood, Andrew I.

doi:10.1016/j.toxicon.2004.08.020

Cited by 190 publications

(180 citation statements)

References 24 publications

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“…Thus, coastal and inland marine measurements [24][25][26] collected off the west coast of the continental U.S. were considered more representative of severe HAB scenarios and were used in this analysis (Table 1). However, dissolved toxin concentrations for OA and YTX were compiled from work by Mackenzie and co-workers [27], which were collected off the coast of New Zealand (Table 1). Only dissolved concentrations obtained by grab sampling as opposed to passive sampling methods (SPATT) were included in this analysis given that it is not currently possible to directly compare or extrapolate SPATT measurements (µg/g resin) to ambient concentrations (µg/L).…”

Section: Algal and Toxins Concentrationsmentioning

confidence: 99%

Investigation of Algal Biotoxin Removal during SWRO Desalination through a Materials Flow Analysis

Manheim

Jiang

2017

Water

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Abstract:The operation of seawater reverse osmosis (SWRO) desalination facilities has become challenged by the increasing frequency and severity of harmful algal blooms (HABs). The efficiency of algal toxins removal during SWRO and pretreatment processes has critical human health implications. Therefore, a probabilistic materials flow analysis (pMFA) was developed to predict the removal of algal toxins in source water by various pretreatment configurations and operations during SWRO desalination. The results demonstrated that an appreciable quantity of toxins exists in the SWRO permeate (ng/L-µg/L levels), the backwash of pretreatment, and final brine rejects (µg/L-mg/L levels). Varying the pretreatment train configuration resulted in statistically significant differences in toxin removals, where higher removal efficiencies were evidenced in systems employing microfiltration/ultrafiltration (MF/UF) over granular media filtration (GMF). However, this performance depended on operational practices including coagulant addition and transmembrane pressures of MF/UF systems. Acute human health risks during lifetime exposure to algal toxins from ingestion of desalinated water were benign, with margins of safety ranging from 100 to 4000. This study highlights the importance of pretreatment steps during SWRO operation in the removal of algal toxins for managing marine HABs.

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Section: Algal and Toxins Concentrationsmentioning

confidence: 99%

Investigation of Algal Biotoxin Removal during SWRO Desalination through a Materials Flow Analysis

Manheim

Jiang

2017

Water

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“…These algae-related poisoning can be classified in clinical types: paralytic shellfish poisoning, diarrheic shellfish poisoning and amnesic shellfish poisoning are among the most common. Biotoxins such as okadaic acid, dinophysistoxins, pectenotoxins, yessotoxins, gymnodimine, spirolides, azaspiracids and azaspiracid analogs, domoic acid, mycrocystins and other cyanotoxins, have been successfully detected by MS-based techniques [69][70][71][72][73][74][75].…”

Section: Toxins and Other Environmental Contaminants Detectionmentioning

confidence: 99%

High-Throughput Proteomics: A New Tool for Quality and Safety in Fishery Products

Tedesco¹,

Mullen²,

Cristóbal

2014

CPPS

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Abstract:In order to cope with the increasing demand for fishery products, sensitive technological tools are required to ensure high quality and wholesomeness and to monitor their production process in a sustainable manner while complying with the strict standards imposed by regulatory authorities. Proteomics may assist the industry as it allows an unbiased approach in the discovery of biomarkers that could be used to increase our understanding of different biological, physiological and ecological aspects that may be advantageous in optimizing quality and safety in aquatic species. The aim of this review is to highlight the potential of cost-effective high-throughput technologies, such as those offered by proteomics using "on-line" mass spectrometry to improve the efficiency of the industry in identifying biomarkers relevant for safe high quality products.

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“…Nevertheless, considerable progress has been made toward the use of passive sampling for time-integrated concentrations of algal toxins. MacKenzie et al [34] introduced the first application of passive sampling in algal toxins using a device termed solid-phase adsorption toxin tracking (SPATT), which is conceptually similar to semipermeable membrane device (SPMD) or polar organic chemical integrative samplers (POICS) that have already been used for other trace contaminants in water. The SPATT consists of bags sewn from polyester mesh containing activated polystyrenedivinylbenzene resin, which can adsorb lipophilic toxins dissolved in water.…”

Section: New Sampling and Sample Preparation Techniques For Algal Toxinsmentioning

confidence: 99%

Current Techniques for Detecting and Monitoring Algal Toxins and Causative Harmful Algal Blooms

2014

J Environ Anal Chem

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The detection and monitoring techniques for algal toxins and the causative harmful algal blooms (HABs) are essential for the protection of aquatic lives, shellfish safety, drinking water quality, and public health. Toward the development of fast, easy, and reliable techniques, much progress has been made during the last decade for the qualitative and quantitative analysis of algal toxins. This review highlights the recent progress and new trends of these analytical and monitoring tools, ranging from in-situ quick screening protocols for the monitoring of algal blooms to mass spectrometric analysis of trace levels of various algal toxins and structural elucidation. Solid-phase adsorption toxin tracking (SPATT) deployed in the field for the passive sampling of algal toxins has been recently validated, and improved ELISA-based methods with lower detection limits for more toxins have become commercially available for both screening and routine monitoring purposes. Liquid chromatography-mass spectrometry with several recent mass spectrometric innovations has expanded our understanding of traditional toxins, their metabolites along with newly discovered toxins of ecological importance. Several established in vivo and in vitro bioassays will continue to be used as benchmark toxicological testing of algal toxins; however, newly emerged molecular probing techniques such as real-time quantitative polymerase chain reaction (qPCR) have extended our ability to trace algal toxins from causative organisms at the molecular level. New chemical and biological sensors, lab-on-chip and remote sensing of blooms being developed will hold promise for early warning and routine monitoring to better manage and protect our freshwater, coastal and marine resources from adverse impact by harmful algal blooms.

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Solid phase adsorption toxin tracking (SPATT): a new monitoring tool that simulates the biotoxin contamination of filter feeding bivalves

Cited by 190 publications

References 24 publications

Investigation of Algal Biotoxin Removal during SWRO Desalination through a Materials Flow Analysis

Investigation of Algal Biotoxin Removal during SWRO Desalination through a Materials Flow Analysis

High-Throughput Proteomics: A New Tool for Quality and Safety in Fishery Products

Current Techniques for Detecting and Monitoring Algal Toxins and Causative Harmful Algal Blooms

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