Solid‐phase extraction of drugs with cuttlefish bone powder as a sorbent

Khazri, Hassen; Ghorbel–Abid, Ibtissem; Debrauwer, Laurent; Kalfat, Rafik; Trabelsi‐Ayadi, Malika

doi:10.1002/jssc.201800419

Cited by 7 publications

(5 citation statements)

References 11 publications

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“…The best recovery for most of the compounds obtained with a volume of 200 mL. However, in our previous work it was shown that per cent recoveries tend to decrease when loading large sample volumes (500 mL) into the SPE cartridge .…”

Section: Resultsmentioning

confidence: 88%

Clay‐Na as a sorbent for the extraction of anti‐inflammatory compounds in water samples

Khazri¹,

Ghorbel–Abid²,

Hassine

et al. 2019

J of Separation Science

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In this work, clay‐Na particles are used as the adsorbent for the solid‐phase extraction of acidic compounds. The novel sorbent under study is based on high‐specific surface area, cation‐exchange capacity designed specifically to offer ion‐exchange properties with the goal being to selectively extract a group of acidic compounds. The effects of the extraction parameters including extraction elution solvent, sample volume and pH. In optimum conditions, the repeatability for one fiber (n = 3), expressed as % relative standard deviation, was between 0.3 and 4.3% for the acid compounds. The detection limits for the studied acidic compounds were between 0.1–0.6 μg/L. The developed method offers the advantages of being simple to use and having a low cost of equipment.

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Section: Resultsmentioning

confidence: 88%

Clay‐Na as a sorbent for the extraction of anti‐inflammatory compounds in water samples

Khazri¹,

Ghorbel–Abid²,

Hassine

et al. 2019

J of Separation Science

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“…67-56-1) (6 ml). At the end, an evaporation of these extracts was applied, followed by a reconstitution in methanol (1 ml) as described by Khazri et al (2019b).…”

Section: Quantification Of Carbamazepinementioning

confidence: 99%

Assessment of carbamazepine acute toxicity in the cockle Cerastoderma edule through chemical, physiological and biochemical tools

et al. 2022

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The cockle Cerastoderma edule was exposed to four concentrations (5, 10, 20 and 70 μg L-1) of carbamazepine (CBZ). This anticonvulsant was found to alter the mussel behavior of by reducing its clearance rate (CR). Analysis of CBZ accumulation in tissues of C. edule was carried out using HPLC-UV after 48 or 96 hours of exposure. In addition, an overproduction of H2O2 by the bivalves was detected following exposure to CBZ but nitrite levels remained unchanged. Moreover, superoxide dismutase and catalase activities showed a significant increase in relation to their contact with CBZ. The activity of the biotransformation enzyme gluthatione-S-transferase did not change during exposure. Malondialdehyde (MDA) levels indicating cellular damage, increased when bivalves were exposed to 20 and 70 μg l-1 of carbamazepine for 96 h CBZ. The results also indicate that acetylcholinesterase activity (AChE) was inhibited in all CBZ concentrations during the 48 h exposure period. However, during the 96 h exposure period, AChE was only inhibited at the highest concentration. Further studies are needed now for more exploration of the toxicity of CBZ since it could be bioaccumulable throughout the food web and may affect non-target organisms.

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“…pH plays an important role in the adsorption and extraction of organic compounds in aqueous media [56][57] due to the protonation/deprotonation of both the analyte and the SFGs of the sorbent at different pH [48]. The influence of pH on the extraction recoveries by AC800 was investigated at the pH values of 5.5, 7.5, and 9.5.…”

Section: Effect Of Ph On Recoverymentioning

confidence: 99%

Surface modification of coconut shell activated carbon for efficient solid‐phase extraction of N‐nitrosodimethylamine from water

Astuti

Jasemizad

Padhye

2020

J of Separation Science

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A practical and cheap methodology in modifying commercial coconut shell activated carbon for solid‐phase extraction of N‐nitrosodimethylamine in water was developed through an understanding of activated carbon surface chemistry. In comparison with commercial activated carbon, extraction recoveries by activated carbon treated with sulfuric acid decreased by 50%, while those of activated carbon heated at 800°C improved by more than 100%. Acid treatment increased the oxygen content on the carbon's surface. In contrast, heat treatment decreased the surface oxygen content, resulting in a more hydrophobic surface, which favoured adsorption and extraction of N‐nitrosodimethylamine. The influence of different activated carbon sizes, amount of modified activated carbon, and pH on the N‐nitrosodimethylamine recoveries was assessed and compared with the commercial solid‐phase extraction cartridge. The recommended amount of powder activated carbon treated at 800°C was 3 g to yield an optimum recovery of 130%, which was superior to the commercial solid‐phase extraction cartridges. The method validation results confirmed the high accuracy, reproducibility, and precision of the method. The study indicated that chemisorption plays a significant role in the adsorption of N‐nitrosodimethylamine on activated carbon, and the optimization of its surface chemistry can enhance N‐nitrosodimethylamine adsorption/extraction from water.

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Solid‐phase extraction of drugs with cuttlefish bone powder as a sorbent

Cited by 7 publications

References 11 publications

Clay‐Na as a sorbent for the extraction of anti‐inflammatory compounds in water samples

Clay‐Na as a sorbent for the extraction of anti‐inflammatory compounds in water samples

Assessment of carbamazepine acute toxicity in the cockle Cerastoderma edule through chemical, physiological and biochemical tools

Surface modification of coconut shell activated carbon for efficient solid‐phase extraction of N‐nitrosodimethylamine from water

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