Solid-Phase Extraction of Glyphosate in the Analyses of Environmental, Plant, and Food Samples

Rigobello-Masini, Marilda; Pereira, Erico A. Oliveira; Abate, Gilberto; Masini, Jorge C.

doi:10.1007/s10337-019-03748-3

Cited by 27 publications

(13 citation statements)

References 116 publications

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“…Recently, novel automated sample preparation methods (Table 1) have emerged in the field of metabolomics. These methods are solid-phase extraction (SPE), solid-phase microextraction (SPME), liquid-phase microextraction (LPME) methods (dispersive liquid-liquid microextraction (DLLME), hollow fiber liquid-liquid microextraction (HF-LLME), single drop microextraction (SDME) and the recent electromembrane extraction (EME)), accelerated solvent extraction (ASE), supercritical fluid extraction (SFE), microwave-assisted extraction (MAE) and ultrasound-assisted extraction (UAE) [40,42,43]. The detailed SPME workflow is described in [50].…”

Section: Automation In Sample Preparationmentioning

confidence: 99%

Metabolomics-Guided Elucidation of Plant Abiotic Stress Responses in the 4IR Era: An Overview

et al. 2021

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Plants are constantly challenged by changing environmental conditions that include abiotic stresses. These are limiting their development and productivity and are subsequently threatening our food security, especially when considering the pressure of the increasing global population. Thus, there is an urgent need for the next generation of crops with high productivity and resilience to climate change. The dawn of a new era characterized by the emergence of fourth industrial revolution (4IR) technologies has redefined the ideological boundaries of research and applications in plant sciences. Recent technological advances and machine learning (ML)-based computational tools and omics data analysis approaches are allowing scientists to derive comprehensive metabolic descriptions and models for the target plant species under specific conditions. Such accurate metabolic descriptions are imperatively essential for devising a roadmap for the next generation of crops that are resilient to environmental deterioration. By synthesizing the recent literature and collating data on metabolomics studies on plant responses to abiotic stresses, in the context of the 4IR era, we point out the opportunities and challenges offered by omics science, analytical intelligence, computational tools and big data analytics. Specifically, we highlight technological advancements in (plant) metabolomics workflows and the use of machine learning and computational tools to decipher the dynamics in the chemical space that define plant responses to abiotic stress conditions.

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Section: Automation In Sample Preparationmentioning

confidence: 99%

Metabolomics-Guided Elucidation of Plant Abiotic Stress Responses in the 4IR Era: An Overview

et al. 2021

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“…MIPs reduce interferences and matrix effects during sample preparation, and result in selective and precise analytical methods by enhancing chromatographic separation and detection. MIPs’ exceptional efficiency has also been utilized in the analysis of glyphosate residues in water samples [ 28 , 29 ]. However, MIPs have not yet been tested in complex matrices such as beebread.…”

Section: Introductionmentioning

confidence: 99%

Method of Glyphosate, AMPA, and Glufosinate Ammonium Determination in Beebread by Liquid Chromatography—Tandem Mass Spectrometry after Molecularly Imprinted Solid-Phase Extraction

Małysiak

Kiljanek

2022

Molecules

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The aim of this study was to develop a method for the determination of glyphosate, its metabolite aminomethylphosphonic acid (AMPA), and glufosinate ammonium residues in beebread samples, which could then be used to assess bees’ exposure to their residues. The complexity of beebread’s matrix, combined with the specific properties of glyphosate itself, required careful selection and optimization of each analysis step. The use of molecularly imprinted solid-phase extraction (MIP-SPE) by AFFINIMIP glyphosate as an initial clean-up step significantly eliminated matrix components and ensured an efficient derivatization step. Colorless beebread extracts were derivatized by the addition of 9-fluorenylmethyl chloroformate (FMOC-Cl). After derivatization, in order to remove FMOC-OH and residual borate buffer, a solid-phase extraction (SPE) clean-up step using Oasis HLB was carried out. Instrumental analysis was performed by liquid chromatography coupled with tandem mass spectrometry (LC–MS/MS). The method was validated according to the SANTE/11312/2021 guideline at concentrations of 5, 10, and 100 µg/kg, and satisfactory recovery (trueness) values (76–111%) and precision (RSDr) ≤ 18% were obtained. The limit of quantification (LOQ) was 5 µg/kg for AMPA and glufosinate ammonium and 10 µg/kg for glyphosate. The method was positively verified by the international proficiency test. Analysis of beebread samples showed the method's usefulness in practice. The developed method could be a reliable tool for the assessment of beebread’s contamination with residues of glyphosate, its metabolite AMPA, and glufosinate ammonium.

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“…Solid-phase extraction (SPE) is a popular and practical sample preparation technique due to its high recovery, high enrichment factor, wide applicable range for organic analytes (from nonpolar to very polar analytes), and ease of T h i s c o n t e n t i s The enrichment sorbents of GLYP are based on either ion exchange or partitioning of its derivatives on nonpolar sorbents. 3 However, the methods are poorly selective toward GLYP in the presence of compounds of a similar chemical nature, thus causing interference in the derivatization and detection steps. Molecularly imprinted polymers (MIPs) have received great attention in recent decades in many scientific areas, such as chemical sensors, 4−7 chromatographic stationary phases, 8,9 and SPE sorbents.…”

Section: Introductionmentioning

confidence: 99%

“…The enrichment sorbents of GLYP are based on either ion exchange or partitioning of its derivatives on nonpolar sorbents . However, the methods are poorly selective toward GLYP in the presence of compounds of a similar chemical nature, thus causing interference in the derivatization and detection steps.…”

Section: Introductionmentioning

confidence: 99%

Magnetic Molecularly Imprinted Polymer for the Selective Enrichment of Glyphosate, Glufosinate, and Aminomethylphosphonic Acid Prior to High-Performance Liquid Chromatography

Surapong

Burakham

2021

ACS Omega

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A novel mixed iron hydroxide molecularly imprinted polymer (MIH-MIP) was synthesized via polymerization using mixed-valence iron hydroxide as a magnetic supporter, glyphosate as a template, acrylamide as a functional monomer, and ethylene glycol dimethacrylate as a cross-linker. The resulting material was characterized and applied as a sorbent for the selective enrichment of glyphosate, aminomethylphosphonic acid, and glufosinate by magnetic solid-phase extraction (MSPE) prior to high-performance liquid chromatography. MIH-MIP possessed a high adsorption capacity in the range of 2.31–5.40 mg g–1 with good imprinting factors ranging from 1.52 to 7.59. The Langmuir model proved that the recognition sites were distributed as a monolayer on the surface of MIH-MIP. Scatchard analysis showed two types of binding sites on MIH-MIP. The kinetic characteristics of MIH-MIP suggested that the binding process of all analytes fit well with the pseudosecond-order model. The developed methodology provides good linearity in the range of 72.0–2000.0 μg L–1. Low detection limits of 21.0–22.5 μg L–1 and enrichment factors of up to 18 were achieved. The precision in terms of relative standard deviations of the intra- and interday experiments was better than 7 and 9%, respectively. The applicability of the developed MSPE facilitates the accurate and efficient determination of water, soil, and vegetable samples with satisfactory recoveries in the range of 86–118%. The results confirmed the suitability of the MIH-MIP sorbent for selective extraction and quantification of glyphosate, aminomethylphosphonic acid, and glufosinate.

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Solid-Phase Extraction of Glyphosate in the Analyses of Environmental, Plant, and Food Samples

Cited by 27 publications

References 116 publications

Metabolomics-Guided Elucidation of Plant Abiotic Stress Responses in the 4IR Era: An Overview

Metabolomics-Guided Elucidation of Plant Abiotic Stress Responses in the 4IR Era: An Overview

Method of Glyphosate, AMPA, and Glufosinate Ammonium Determination in Beebread by Liquid Chromatography—Tandem Mass Spectrometry after Molecularly Imprinted Solid-Phase Extraction

Magnetic Molecularly Imprinted Polymer for the Selective Enrichment of Glyphosate, Glufosinate, and Aminomethylphosphonic Acid Prior to High-Performance Liquid Chromatography

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