Solid-phase extraction using molecularly imprinted polymers for selective extraction of a mycotoxin in cereals

Current Trends in Sample Treatment Techniques for Environmental and Food Analysis

“…In both cases, very reliable baselines and similar recoveries were obtained, proving that the high selectivity of immunoaffinity sorbents also can be achieved with molecularly imprinted polymers SPE. Furthermore, previous studies have found MIP-SPE to have a similar selectivity but a higher capacity than commercial IAC columns [49,55]. These aspects are highly attractive for matrix clean-up, enrichment and selective extraction of analytes in difficult samples that are very common to food and environmental analyses.…”

“…In the off-line mode, MIP-SPE has been applied for the selective extraction and preconcentration of a wide range of analytes, such as mycotoxins in cereal samples [55], thiamphenicol in milk and honey samples [61], domoic acid from seafood [58], ofloxacin and lomefloxacin in chicken muscle [72], pyrethroid insecticides in aquaculture seawater [63] and parabens in soil and sediment samples [70]. Furthermore, MIP-SPE has been applied not only for the extraction of single target analyte but also for the simultaneous isolation of a class of structurally related compounds such as catechins or estrogens from real samples [8,59].…”

Effect of the mimic structure on the molecular recognition properties of molecularly imprinted polymers for ochratoxin A prepared by a fragmental approach

“…In the past, several examples of MIPs binding the mycotoxin Ochratoxin A (OTA, 1) have been published [6][7][8], and this mycotoxin has been frequently considered as target analyte for MISPE of complex samples [9][10][11][12][13][14][15]. When taken into consideration, the problem of polymer bleeding has been successfully addressed by using the rationally designed mimic N-(4-chloro-1-hydroxy-2-naphthoylamido)-(L)-phenylalanine (CHNA-Phe, 3) as a template molecule [6].…”

The performance optimization and specific adsorption of L-phenylalanine imprinted polymers using 1-vinyl-3-carboxymethylimidazolium chloride as functional monomer

“…Compared to natural recognition materials, molecularly imprinted polymers (MIPs) have some advantages such as excellent ability of recognition, stability, and easy preparation. Thus, MIPs have attracted considerable attention in many fields, [7][8][9][10][11][12] such as separations, [13][14][15][16] catalysis, [17,18] biosensors, [19] and the development of biomedical materials. [20,21] In recent years, molecular imprinting technique as a promising technique was used for the separation of amino acids and chiral compounds, [22] providing a new and effective way for chiral separation.…”