Solid-Phase Organic Synthesis of 1-(E)-Phenylethenyl-4-Substituted-1,2,3-Triazoles from Polystyrene-Supported (2-Azido-1-Phenyl)Ethyl Selenide

Abstract

A facile method for solid-phase organic synthesis of 1-(E)-phenylethenyl-4-substituted-1,2,3-triazoles from polystyrene-supported (2-azido-1-phenyl)ethyl selenide and substituted ethynes has been developed. The advantages of this method include straightforward operation, high yield and purity of the products, as well as lack of odour and good stability of the polymeric reagent.