Solid Pseudopapillary Tumor of the Pancreas in a Young Woman - Case Report

Abstract

We report a case of pancreatic solid pseudopapillary tumor that was diagnosed in a 36-year-old female patient. This neoplasm usually occurs in young women. Solid and cystic areas form a characteristic appearance of this tumor. Surgical resection is the mainstay of treatment and is possible in the majority of cases. Neoplasm is associated with a low-grade malignancy and a very good outlook.

Solid-Pseudopapillary tumor of the pancreas: Clinical and radiological features. Case report and review of the literature

“…Even more unusual is, its presentation as an acute abdomen symptom with hemoperitoneum from spontaneous rupture or intratumoral bleeding [23][24][25][26][27][28][29]. They commonly located in the body and tail of pancreas also like our patient [1][2][3][4][5][6][7]11,12,18]. In the review of Peng-Fei Yu et al 43.6% of tumors were localized in the body and tail of the pancreas [12].…”

“…SPTs of the pancreas are unusual neoplasms of the pancreas of uncertain histogenesis that occur mostly, but not exclusively in young women in the second or third decade. It is a rare neoplasm that has shown a progressive increase of incidence, passing from 0.17% -2.7% of 711 exocrine tumors of the pancreas in the 1980's, to 6% in recent report in 2003 [1][2][3][4][5][6][7][8][9][10]. Until 2006, there have been 718 cases in the English literature: female dominance has been found with a ratio of 10:1 and there was a mean age of 22 years [11].…”

“…The histogenesis of these epithelial neoplasms remains unclear. They have been suggested to have a ductal epithelial, neuroendocrine multipotent primordial cell, or even an extra pancreatic genital related cell origin [2,3,7,[12][13][14][15][16][17]. Deshpande et al have described three cases of SPT of the ovary that resembling those of the pancreas [15].…”

“…They are slow growing tumors with indolent course as was seen in our case. The diagnosis in most cases is based on compressive symptoms, pain or finding of a palpable mass, while about 20% to 30% of the patients, the diagnosis is made during abdominal imaging performed for others pathologies [1][2][3]5,7,12,13,[18][19][20][21][22]. Even more unusual is, its presentation as an acute abdomen symptom with hemoperitoneum from spontaneous rupture or intratumoral bleeding [23][24][25][26][27][28][29].…”

“…Solid-Pseudopapillary Tumor (SPT) of the pancreas or Frantz tumor is a rare exocrine neoplastic tumor of the pancreas with a high prevalence in young women. It accounts for 0.13% -2.7% of all pancreatic tumors and it's generally considered as a tumor with a low malignant potential [1][2][3][4]. Although resection of the tumor provides a 5-year survival rate of 97%, local recurrence or distant metastases can occur in a significant number of patients [1,2,[5][6][7][8].…”