Solid structure and biodegradation of the compositionally fractionated poly(3-hydroxybutyric acid-co-3-hydroxypropionic acid)s

Biosynthesis and Biodegradation of 3-Hydroxypropionate- Containing Polyesters

“…Shimamura et al (39) degraded poly(3HB-co-3HP) films with different 3HP contents with PhaZ Rp . These results, in addition to those of Cao et al (8), suggested that the rates of enzymatic degradation were controlled not only by the crystallinity of the polymer but also by the chemical structure of the building blocks and the substrate specificity of PHA depolymerases. The crystalline structure and the degree of crystallinity of poly(3HB-co-3HP) copolymers were shown to change with alterations in the 3HP content.…”

Comparative Study of Effects of Thio/Oxo Ester Linkages on Thermal Properties of Bacterial Poly[3-hydroxybutyrate-co-3-(mercapto/hydroxy)propionate]s

“…It has been reported that P(3HB-co-3HP)s with higher 3HB unit content form the P(3HB) homopolymer type crystalline lattice and only the 3HB units are included in the crystalline phase. 8,12,13 Thus, it is reasonable to consider that P(3HB-co-3MP)s with higher 3HB unit content also form similar P(3HB) homopolymer-type crystalline lattice, and the 3MP units are excluded from the crystalline phase.…”

“…[3][4][5] For example, a series of poly(3-hydroxybutyrate-co-3-hydroxypropionate)s [P(3HB-co-3HP)s] 6-8 and poly(3-hydroxybutyrateco-3-hydroxyvalerate)s [P(3HB-co-3HV)s]. [9][10][11] It has been known that the bacterially as-produced copolymers, such as P(3HB-co-3HP) 8,12,13 and P(3HB-co-3HV), [9][10][11]14 have a broad comonomer unit compositional distribution, and they are practically mixtures(blends) of random copolymers having different comonomer unit composition. It has been found that solid-state structures and properties of bacterial copoly(hydroxyalkanoate)s depend not only on their chemical structures but also on their comonomer unit compositional distribution.…”

“…It has been found that solid-state structures and properties of bacterial copoly(hydroxyalkanoate)s depend not only on their chemical structures but also on their comonomer unit compositional distribution. [6][7][8][9][10][11][12][13][14][15] Recently, poly(3-hydroxybutyrate-co-3-mercaptopropionate) [P(3HB-co-3MP)] has been bacterially synthesized. [16][17][18] It was the first example on a bacterial PHA containing sulfur atoms in the backbone.…”

Enzymatic Hydrolysis of Thioester Linkages in Bacterial Poly(3-hydroxybutyrate-co-3-mercaptopropionate)s by Poly(3-hydroxybutyrate) Depolymerase Isolated from Ralstonia pickettii T1

“…One of major approaches to modify the bacterial poly(3-hydroxybutyrate) (PHB) while reserving its biodegradability has involved the copolymerization of its monomer with some hydroxyalkanoates (HA) via bacterial fermentation, 1 comprising 3-, 4-, 5-and 6-hydroxyalkanoates with various length of the mainchain or various substituents at different positions, such as 3-hydroxypropionate (3HP), [2][3][4][5] 3-hydroxyvalerate (3HV) 6,7 and so forth. Recently, Steinbüchel's group [8][9][10][11][12][13][14] has succeeded to isolate a novel class of biopolymers from the poly-(hydroxyalkanoate) (PHA)-accumulating bacterium, comprising one kind of completely different backbone constituents, that is, thioesters, such as poly(3-mercaptopropionate), poly(3-mercaptobutyrate), poly(3-mercaptovalerate), poly(3-hydroxybutyrate-co-3-mercaptopropionate) [P(3HB-co-3MP)] and poly(3-hydroxybutyrate-co-3-mercaptobutyrate).…”