Solitary extramedullary plasmacytoma in retroperitoneum: A case report and review of the literature

Abstract

Extramedullary plasmacytoma (EPM) is a plasma cell tumor arising outside of the bone marrow. Solitary EMP is an uncommon neoplasm and rarely occurs in the retroperitoneum and lacks distinctive clinical manifestations. We report a 26-year-old man with a solitary EMP in the retroperitoneum and discuss its clinical features, diagnosis and treatment.

Post‐renal transplant plasma cell dyscrasia presenting as retroperitoneal plasmacytoma: A case report and literature review

“…Our review of the literature revealed very few cases of retroperitoneal plasmacy‐toma in general and among renal transplant recipients in particular. To our knowledge, this could be the first case of retroperito‐neal plasmacytoma in a renal transplant recipient 11–14…”

A case of disseminated recurrent retroperitoneal plasmacytoma with left obstructive hydronephrosis

“…EMP should be suspected in cases when a retroperitoneal mass is identified 5. CT scan with/without positron emission tomography scan or MRI may show evidence of mass at the specific location and its extension.…”

“…CT scan with/without positron emission tomography scan or MRI may show evidence of mass at the specific location and its extension. Definitive diagnosis requires histopathological examination of the biopsied specimen and immunohistochemistry 5 6. Immunohistochemistry not only supports the diagnosis but also helps in ruling out other diagnoses such as lymphoplasmacytic lymphoma and immunoblastic lymphoma 8.…”

“…Although highly radiosensitive, radiotherapy to a large retroperitoneal plasmacytoma is associated with significant morbidity 5. Current literature supports use of radiotherapy11 12 or combined radiotherapy and surgery depending on the resectability of the tumour7 13 or combined radiotherapy and chemotherapy 14.…”

“…A high index of suspicion is required for the diagnosis of this condition at an earlier stage. Small and confined EMPs are usually highly radiosensitive 4 5…”