Solitary extramedullary plasmocytoma of the liver

Husaric, Senada; Pašić, Jasmina; Alić, Enisa; Kuljanin, Maida

doi:10.5644/ama2006-124.76

Cited by 5 publications

(4 citation statements)

References 2 publications

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“…The age range was 26-77 years, with a median age of 57 years (table 1). This is consistent with our knowledge of EMP presenting elsewhere in the body; males in the sixth and seventh decades are more likely to develop EMP than females [1,2].…”

Section: Patient Characteristics and Clinical Featuressupporting

confidence: 92%

“…EMP accounts for 3% of all plasma cell malignancies and approximately 80% of these cases are found in the aerodigestive tract of the head and neck but may also occur in the GI tract, urinary bladder, CNS, thyroid, breast, testes, parotid gland, lymph nodes and skin [1]. Males are three-times more likely than females to develop EMP and it is typically found in adults in their 50s and 60s with a median age of 55 [1,2]. There are no typical clinical manifestations of adrenal plasmacytomas.…”

Section: Discussion and Reviewmentioning

confidence: 99%

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Bilateral Extramedullary Adrenal Plasmacytoma: Case Report and Review of the Literature

Townend

Kraus

Coyle

et al. 2017

Int. J. Endo. Oncol.

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Extramedullary plasmacytoma (EMP) accounts for only 3% of plasma cell malignancies; others include multiple myeloma, plasma cell leukemia and solitary plasmacytoma of bone. The majority of EMPs are found in the upper respiratory tract. Other sites include the GI tract, bladder, CNS, thyroid, breast, testes, parotid gland, lymph nodes and skin. There are eight cases in the literature of adrenal plasmacytoma, however, only two were bilateral. We describe our recent experience of bilateral adrenal plasmacytoma and review of the literature. While EMP may present as aggressive locally destructive lesions, excellent local control can be achieved in a majority of cases. Follow-up should be lifelong due to risk of progression to multiple myeloma.

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Section: Patient Characteristics and Clinical Featuressupporting

confidence: 92%

Section: Discussion and Reviewmentioning

confidence: 99%

Bilateral Extramedullary Adrenal Plasmacytoma: Case Report and Review of the Literature

Townend

Kraus

Coyle

et al. 2017

Int. J. Endo. Oncol.

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“…Gastrointestinal, lung, bladder, and testis involvement have also been reported. Only a few cases of hepatic SP have been reported to date [3, 4]. The presence of plasma cells in the liver or spleen is known to be associated with a more aggressive form of multiple myeloma [3] that usually requires a heavy treatment with chemotherapy or consolidation therapy with autologous hematopoietic stem cell transplantation.…”

Section: Introductionmentioning

confidence: 99%

Primary solitary plasmacytoma of the liver – successful treatment with fractionated stereotactic radiotherapy (Cyberknife®): a case report

Chalopin

Barillot

Biny³

et al. 2017

J Med Case Reports

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BackgroundSolitary plasmacytoma of the liver is a very rare and aggressive form of plasma cell dyscrasia. To the best of our knowledge, very few cases have been reported without systemic disease. We reported a rare case of hepatic solitary plasmacytoma that successfully responded to fractionated stereotactic radiotherapy.Case presentationA 64-year-old white French man had monoclonal gammopathy of the immune globulin G lambda type; he developed a cholestasis and cytolysis with the discovery of a subscapular nodule. A biopsy showed plasma cells and, for several reasons, the decision was made to use the fractionated stereotactic radiotherapy strategy. After 20 months, he is asymptomatic and the immune globulin G component has completely disappeared.ConclusionWe suggest considering Cyberknife® radiosurgery as an option for the treatment of hepatic solitary plasmacytoma.

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“…Additionally, 80% of such lesions are located in the head and neck region (2). A paucity of data exists concerning the presentation, natural course and outcome of EMP, however, Xing et al (3) reviewed 147 cases of EMP of the larynx.…”

Section: Introductionmentioning

confidence: 99%

Retroperitoneal laparoscopic management of a solitary extramedullary plasmacytoma associated with human immunodeficiency virus infection: A case report

Cao

et al. 2015

Oncology Letters

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Abstract. Extramedullary plasmacytoma (EMP) is a rare malignant tumor that is characterized by a malignant plasma cell neoplasm. Such neoplasms in human immunodeficiency virus (HIV)-infected patients are extremely rare. To the best of our knowledge, the present study describes the first case of a solitary adrenal EMP in a patient with HIV. A 35-year-old male who had been diagnosed with HIV 3 months previously presented with a 2-week history of intermittent right flank pain. Abdominal computed tomography revealed a soft-tissue density mass in the right adrenal gland area. The patient subsequently underwent a retroperitoneal laparoscopic adrenalectomy. Post-operative pathological diagnosis revealed a solitary EMP. Although the patient refused to undergo post-operative radiotherapy and chemotherapy, no recurrence was detected after 2 years of follow-up. The present case illustrates the fact that this rare type of solitary EMP associated with acquired immune deficiency syndrome (AIDS) can occur in the adrenal glands, and that retroperitoneal laparoscopic resection of the tumor may be a good method to manage this condition. In addition, although rare, solitary EMP should be considered in the differential diagnosis of an adrenal mass in HIV-infected patients.

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Solitary extramedullary plasmocytoma of the liver

Cited by 5 publications

References 2 publications

Bilateral Extramedullary Adrenal Plasmacytoma: Case Report and Review of the Literature

Bilateral Extramedullary Adrenal Plasmacytoma: Case Report and Review of the Literature

Primary solitary plasmacytoma of the liver – successful treatment with fractionated stereotactic radiotherapy (Cyberknife®): a case report

Retroperitoneal laparoscopic management of a solitary extramedullary plasmacytoma associated with human immunodeficiency virus infection: A case report

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