Solitary Fibrous Tumor in the Pelvic Cavity with Hypoglycemia: Report of a Case

Solitary fibrous tumors (SFT) of extremities, especially the thighs are very rare. Despite SFTs are generally benign, well-circumscribed soft tissue tumors new cases should be presented and followed up carefully to monitor their biological behavior. In general for tumor classification a biopsy is state of the art. Histological including immunohistochemical patterns for SFTs are defined. MRI and ultrasound are not sufficient for differential diagnosis. Once property identified and defined by size and location, resection with intact tumor capsule may result in full recovery of the patient. Reviewing the literature there are no validated reasons for a wider resection. The current patient was a 41-year-old male. Four years after an arthroscopy of the left knee the patient has been suffering an ongoing swelling of the lateral thigh. Because MRI scan data suggested a synovial sarcoma a biopsy was performed. The tumor was classified as a benign SFT. The diagnosis based on histological findings and the presence of the positive immunohistochemical markers Vimentin, CD34, and CD99. The complete tumor resection with intact capsule was achieved in a final operation. Clinical and in MRI after 54-month outcome period there were no local recurrences.

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“…Preoperative rarely seen hypoglycemia disappeared after en bloc excision of the tumor (Nagase et al 2005).…”

Section: Therapymentioning

confidence: 98%

Solitary fibrous tumor in the thigh: review of the literature

Anders

Aurich

Lang

et al. 2005

J Cancer Res Clin Oncol

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“…Most SFTs in deep soft tissue are indolent and are found incidentally in the course of examinations for other disorders or during medical check-ups. Some cases are also diagnosed with hypoglycemia, due to insulin-like growth factor Ⅱ (IGF-2) secreted by the tumor cells of SFT (4). In the present case, SFT was found in the pelvis, with urinary retention caused by tumor pressure on the urethra.…”

Section: Introductionmentioning

confidence: 63%

“…CT imaging of SFT usually revealed a well-delineated, homogeneous, and occasionally lobulated mass of soft tissue attenuation (7), and MRI revealed fibrous tissue of SFT with a low signal intensity on T1-weighted images. However, mature fibrous tissue has a low intensity, while malignant fibrous tissue tends to exhibit a high signal intensity on T2-weighted images (4). Although the radiological findings in our case were typical of SFT, we performed US-guided needle biopsy for diagnosis since cases of SFT are rare.…”

Section: Discussionmentioning

confidence: 99%

Surgical resection using retroperitoneal approach for solitary fibrous tumor in the pelvis

et al. 2011

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Abstract. This report concerns a case of solitary fibrous tumor (SFT) for which surgical resection was performed using a retroperitoneal approach. A 41-year-old man was referred to our hospital with urinary retention. Abdominal ultrasound sonography (US) and computed tomography (CT) showed a hypervascular mass lesion in the pelvis. Transrectal biopsy showed SFT. Surgical resection was carried out using a retroperitoneal approach and preserving the neural network related to urinary and erectile functions. Based on immunohistochemical findings, the tumor was diagnosed to be malignant SFT in the pelvic cavity. Urinary function improved post-operation. There was no change to IIEF-5 and it continued to function well. The patient showed no sign of recurrence 12 months after surgery and required no additional therapy.

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“…It can reach over 10cm diameter, that can cause pressure and dysfunction of different organs. Sometimes it can give paraneoplastic signs as hypoglicemy because of insulin-like growth factor (IGF) secretion (7). The most common extra-pleural localisation is retroperitoneal and peritoneal space, soft tissues of extremities and head.…”

Section: Discussionmentioning

confidence: 99%

Gigantic Solitary Fibrous Tumour of Extra-Peritoneal Space. A Case Report and Review of the Literature

Guzel¹,

Dąbrowski²,

Mazurkiewicz³

et al. 2014

Polish Journal of Surgery

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Solitary fibrous tumour (SFT) is a rare soft tissue tumour which belongs to fibroblastic/myofibroblastic group of tumours. The most often it appears in pleura, also in pericardium, internal organs, peritoneum and extraperitoenal space. SFT was first described as a new type of pleura's tumour by Klemperer and Rabin in 1931. The histogenesis of SFT's has been discussed for years suggesting its mesothelial origin. Recently, SFT has been classified as a mesenchymal fibroblastic tumour. We report a very rare case of 71-year old man suffering from gigantic solitary fibrous tumour of extraperitoneal space who underwent curative surgery in the Department of General, Gastroenterological and Oncologic Surgery in 2011.

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Solitary Fibrous Tumor in the Pelvic Cavity with Hypoglycemia: Report of a Case

Cited by 32 publications

References 14 publications

Solitary fibrous tumor in the thigh: review of the literature

Solitary fibrous tumor in the thigh: review of the literature

Surgical resection using retroperitoneal approach for solitary fibrous tumor in the pelvis

Gigantic Solitary Fibrous Tumour of Extra-Peritoneal Space. A Case Report and Review of the Literature

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