2023
DOI: 10.1177/10668969231199165
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Solitary Fibrous Tumor of the Kidney With Pure Round Cell Features: A Case Report With Review of Literature

Anandi Lobo,
Shilpy Jha,
Rahul Kapoor
et al.

Abstract: Solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm known to occur at various soft tissue and visceral locations. Kidney is a rarely reported site for these tumors. Most of the SFTs described in the kidney exhibit a classical CD34-positive patternless spindle cell histology. Focal round cell morphology is seldom reported. Herein, we describe a 48-year-old male patient with renal SFT. This tumor had pure round cell morphology with a CD34−/STAT6+ immunophenotype. Fluorescent in situ hybridization and a m… Show more

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“…Our case of renal SFT showed increased cellularity and exhibited an ovoid cytomorphology rather than the classic spindly nature. The STAT6+, BCOR+, CD99+, and CD34 negative immunohistochemical profile seen in our case has been reported by Argani et al and Lobo et al to be associated with high-grade/dedifferentiated features [ 3 , 18 ]. Hypercellularity with round cell features is considered a high-grade feature and is observed in 48% of CD34-negative SFTs [ 6 ].…”
Section: Discussionsupporting
confidence: 83%
“…Our case of renal SFT showed increased cellularity and exhibited an ovoid cytomorphology rather than the classic spindly nature. The STAT6+, BCOR+, CD99+, and CD34 negative immunohistochemical profile seen in our case has been reported by Argani et al and Lobo et al to be associated with high-grade/dedifferentiated features [ 3 , 18 ]. Hypercellularity with round cell features is considered a high-grade feature and is observed in 48% of CD34-negative SFTs [ 6 ].…”
Section: Discussionsupporting
confidence: 83%