Solitary fibrous tumor of the pleura with marked cystic degeneration: a case report

Abstract

Background Solitary fibrous tumor of the pleura (SFTP) is a mesenchymal tumor, and computed tomography typically shows SFTPs as well-defined lobulated masses. We herein report a case of SFTP with cystic degeneration of the entire tumor. Case presentation The patient was a 67-year-old Japanese man who was referred to our hospital for an abnormal shadow on a chest X-ray. Computed tomography showed a 9-cm cystic tumor in the lower left lobe, with small nodules aggregated in the cyst. Pulmonary aspergillosis was suspected, and left basal segmentectomy was performed. A pedunculated cystic tumor was connected to the pleura with a stalk, and white polypoidal masses were found within the cystic tumor. Microscopy revealed uniform fibroblastic spindle cell proliferation and marked cystic degeneration, the cyst walls were formed of the same tumor cells. Immunohistochemical staining revealed that the tumor cells were positive for CD34, CD99, and BCL2. Based on these findings, the tumor was diagnosed as SFTP with cystic degeneration. Conclusion We experienced an extremely rare case of atypical SFTP with cystic degeneration.

Multiple solitary fibrous tumors of the pleura with multicentric and unilateral involvement: a case report

“…To the best of our knowledge, this is the first case report of SFTPs with unilateral and multicentric. We also reported a rare case of atypical SFTP with cystic degeneration [ 17 ] and describe another rare case of SFTP with multiple, multicentric, and unilateral lesions in the present report. Based on these experiences, it seems that there is still uncharted territory in SFTP.…”

Multicystic Solitary Fibrous Tumor of the Kidney: A Case Report With Review of Literature

“…The cut surfaces are usually solid, firm, and tan-white to yellow in appearance with foci of hemorrhagic, cystic, or myxoid degeneration. Although cystic SFTs have been reported in the orbit and pleura, [10][11][12] a predominantly cystic SFT as a multiloculated and multicystic mass in the kidney has never been reported in the literature. Grossly, other cystic renal neoplasms such as clear cell renal cell carcinoma with cystic change, cystic nephroma, multilocular cystic renal neoplasm of low malignant potential, mixed epithelial and stromal tumor, tubulocystic carcinoma, and angiomyolipoma with epithelial cysts are considered as differentials.…”