Solitary fibrous tumour of the parotid gland: a case report and a 15-year literature review

Lim, Deborah Wan Jun; Tan, Terry Soon Heng; Tan, Jasmine; Venkateswaran, Kotamma

doi:10.21037/acr.2019.04.05

Cited by 10 publications

(16 citation statements)

References 30 publications

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“…Most cases of SFT reported in the literature have been resected without a prior FNA 2‐5,7 . In this case, we demonstrate the challenges for the cytopathologist on ROSE with a retrospective review of the cytomorphological findings.…”

Section: Discussionmentioning

confidence: 85%

“…The most common spindle cell lesions of the salivary gland are myoepithelial‐predominant pleomorphic adenoma, myoepithelioma, schwannoma, and less frequently, nodular fasciitis, solitary fibrous tumour (SFT), myoepithelial carcinoma, spindle cell carcinoma, and melanoma 1 . Approximately forty cases of SFTs have been reported in the parotid gland over the past 17 years, 5 cases in the submandibular gland, and 1 in the sublingual gland 2‐7 …”

Section: Introductionmentioning

confidence: 99%

“…The few cases of SFT of the submandibular gland reported in the literature have been surgically removed with rare recurrence, malignant transformation, or metastasis 2‐7 . The preferred treatment strategy for SFTs is complete surgical resection.…”

Section: Introductionmentioning

confidence: 99%

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Solitary fibrous tumour of the submandibular gland: Novel insights from clinical practice on a close mimicker of pleomorphic adenoma and a diagnostic challenge for the cytopathologist

González

Husain

2020

Cytopathology

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Spindle cell lesions of the salivary glands are rare and account for less than 3% of the salivary gland aspirates. A definitive classification of salivary gland neoplasms by fine needle aspiration is possible for the most common lesions but remains a challenge for the less common entities. We present a case of a 72‐year‐old male with a solitary fibrous tumour (SFT) of the submandibular gland mimicking a myoepithelial‐rich pleomorphic adenoma (PA). In this article, we discuss novel insights that help differentiate SFT from PA and other spindle cell lesions.

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Section: Discussionmentioning

confidence: 85%

Section: Introductionmentioning

confidence: 99%

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Solitary fibrous tumour of the submandibular gland: Novel insights from clinical practice on a close mimicker of pleomorphic adenoma and a diagnostic challenge for the cytopathologist

González

Husain

2020

Cytopathology

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“…From 2012 to 2016, seven more additional cases were published [ 25 – 30 ]. In 2019, Lim et al reviewed all reported cases of SFT in the major salivary glands, including the parotid area, from 2004 to 2018 [ 33 ]. Thus, including our case, only 36 cases have been reported to date.…”

Section: Discussionmentioning

confidence: 99%

Parotid Gland Solitary Fibrous Tumor Presenting as a Long Duration Mass: A Case Report

Abdulhaleem

Dababo

Othman

2022

Case Reports in Pathology

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The solitary fibrous tumor (SFT) is a tumor of uncertain histogenesis, affecting deep soft tissues, particularly the pleura (pulmonary) and extrapulmonary sites including thighs, retroperitoneum, other serosal surfaces, and cranial and spinal meninges. SFT and hemangiopericytoma are now considered the same entity, with general agreement on referring to this group of tumors as “SFT.” SFTs are generally benign tumors with small subsets of malignant ones. Moreover, they are well-circumscribed with a good prognosis after surgical resection. SFTs are uncommon in the head and neck and are quite rare in the parotid gland region. Here, we present a case of a 48-year-old female with SFT of the parotid gland region; the diagnosis was confirmed by positive immunohistochemical staining for Bcl-2, CD34, and STAT6. STAT6 immunohistochemistry is sensitive and specific for SFTs.

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“…Solitary fibrous tumors (SFT) are rare soft tissue tumors that arise from spindle cells of mesenchymal origin and are comprised of small cells with spindle-to-stellate-shaped nuclei separated by thin bands of collagen and a mucinous stroma [1]. Although most commonly observed in the lung pleura, they have been reported in a variety of sites throughout the gastrointestinal tract and associated organs with varying effects on gastrointestinal function, including the esophagus, liver, pancreas, salivary glands, and mesentery, as well as in the spermatic cord, adrenal gland, prostate, and urethra [3][4][5][6][7][8][9][10][11].…”

Section: Discussionmentioning

confidence: 99%

A Novel Cause of Bowel Obstruction in a Patient with Long-Standing Crohn’s Disease

Vedula

Nickerson

Grider

2021

Case Reports in Pathology

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Solitary fibrous tumors are rare tumors of mesenchymal origin. Although most often observed in the lung pleura, they have been reported in varied extrapleural sites. A 70-year-old male with complicated Crohn’s disease presented with 3 days of nausea, emesis, constipation, and abdominal pain. Computed Tomography (CT) demonstrated mucosal thickening of the middescending colon, consistent with fibrosing stricture. Surgical excision revealed an unusual, 5 cm mass originating in the subserosa. Histopathology of the lesion was notable for a proliferation of cells with spindle and stellate-shaped nuclei and no appreciable mitotic figures, which extended into the muscularis and submucosa. Immunohistochemistry was STAT6 nuclear positive and cytoplasmic CD34 positive, diagnostic for solitary fibrous tumor (SFT). In this case, the SFT infiltrating into the muscularis propria and subserosa caused the stricture and bowel obstruction. This illustrates that while fibrosing strictures are usually the etiology of bowel obstruction in the setting of Crohn’s disease, other rare possible causes should be considered.

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Solitary fibrous tumour of the parotid gland: a case report and a 15-year literature review

Cited by 10 publications

References 30 publications

Solitary fibrous tumour of the submandibular gland: Novel insights from clinical practice on a close mimicker of pleomorphic adenoma and a diagnostic challenge for the cytopathologist

Solitary fibrous tumour of the submandibular gland: Novel insights from clinical practice on a close mimicker of pleomorphic adenoma and a diagnostic challenge for the cytopathologist

Parotid Gland Solitary Fibrous Tumor Presenting as a Long Duration Mass: A Case Report

A Novel Cause of Bowel Obstruction in a Patient with Long-Standing Crohn’s Disease

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