Solitary giant neurofibroma of the scalp with calvarial defect in a child

Abstract

Neurofibroma of the scalp are mostly multiple as part of neurofibromatosis or other phakomatosis. De novo solitary types are less common and rarely erode the skull, unlike the intracranial counterpart. Skull erosion has been reported in adults with longstanding plexiform neurofibromas. We report a giant neurofibroma on the scalp of a five-year-old boy, managed in our center. Although this condition is a rare entity, it should be anticipated and the treatment strategy should include repair of the skull defect.

Repair of Occipital Bone Defects in Neurofibromatosis Type 1 by Means of CAD/CAM Prefabricated Titanium Plates

“…NF1 and segmental neurofibromatosis . Similar defects with topographically associated PNF have been reported for patients with generalized neurofibromatosis as well as in some patients whose skeletal/soft-tissue disease has been shown to occur without any further findings that would require the diagnosis of NF1 12162021…”

“…Evidently, most reports are about bone defects in the region of the lambda suture, 3,5-10 but similar osseous lesions are found at the foramen magnum, 11,12 the parietal, [13][14][15] and the frontotemporal region. 16 There were reports of both unilateral 5,17,18 and bilateral 10,15,19 defects of the occiput. An association with a PNF was found in the majority of cases, but was not always present.…”

“…The skeletal defects of the cranial vault in NF1 show a certain regularity in their topography. Evidently, most reports are about bone defects in the region of the lambda suture,35678910 but similar osseous lesions are found at the foramen magnum,1112 the parietal,131415 and the frontotemporal region 16. There were reports of both unilateral51718 and bilateral101519 defects of the occiput.…”

Rapidly growing diffuse neurofibroma of the scalp with calvarial defect in a young woman: A rare entity

“…Skull defect having sclerotic margins is suggestive of an underlying neurogenic tumor. [ 1 ] In this patient, small cranial defect was seen on radiology. Intraoperatively, we found that the cranial defect margins were smooth and were not involved.…”

Scalp Neurofibroma Presenting with Hematoma After Trauma

“…Tanıda Kontrastlı BBT ve MRG önemlidir. Klinik teşhis bu görüntüleme yöntemleri ile doğrulanamayabilir, histopatolojik tanı gerekebilmektedir (7). Tedavide gross total eksizyon hem rekürensi hem de malignite gelişimini engellemektedir.…”