Solitary Intraosseous Neurofibroma of the Frontal Bone  -Case Report-

Yamaguchi, Rei; Yoshida, Taiki; Nakazato, Yoichi; Yoshimoto, Yuhei

doi:10.2176/nmc.50.683

Cited by 6 publications

(5 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Although the diploe can be affected by varying pathologies, intradiploic meningioma has been rarely reported. [1][2][3][4][5][6][7][11][12][13][14][15][16][17][18][19][20][21][22][23][24]26] Furthermore, cerebral angiomatous meningioma is known to be a rare subtype of low-grade meningioma. [9,25] In the present patient, the intradiploic tumor showed a lobular structure on MRI, with intense enhancement of the surrounding dura mater.…”

Section: Discussionmentioning

confidence: 99%

“…[8,13] e diploe can be affected by various pathologies, such as bone cysts, encephaloceles, arachnoid cysts, lipomas, teratomas, dermoid, epidermoid, cavernous hemangiomas, metastatic tumors, neurofibromas, and meningiomas. [1][2][3][4][5][6][7][11][12][13][14][15][16][17][18][19][20][21][22][23][24]26] Intradiploic meningioma is an infrequent but distinct entity that commonly develops as a benign tumor. [1,2,[4][5][6][7]10,12,[16][17][18]20,21,26] Angiomatous meningioma is a rare subtype of the World Health Organization Grade I meningioma, characterized by tumor cells consistent with low-grade meningioma and prominent microvessels of varying sizes.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Calvarial angiomatous meningioma developed in the diploe

Sugiyama

Tsutsumi

Hashizume

et al. 2022

Surgical Neurology International

View full text Add to dashboard Cite

Background: Angiomatous meningioma is a rare subtype of meningiomas. To the best of our knowledge, there have been no reports of intradiploic angiomatous meningioma. Case Description: A 53-year-old previously healthy woman was diagnosed with a calvarial lesion during a brain checkup. Cerebral magnetic resonance imaging showed an intradiploic tumor, 11 × 14 × 12 mm, in the right parietal bone. It was an enhancing, lobular tumor presenting as isointensity on T1- and hyperintensity on T2-weighted sequences, with an intense enhancement of the adjacent dura mater. Computed tomography revealed bone erosion at the tumor site, extending predominantly into the inner side, and sclerotic changes in the surrounding bone. Total resection was performed. Microscopically, the tumor tissue comprised cells with low-grade meningioma and intervening prominent vasculatures, consistent with angiomatous meningioma. Conclusion: Angiomatous meningioma should be considered as a differential diagnosis when an intradiploic tumor shows a lobular structure, intense enhancement of the adjacent dura mater, and sclerotic changes in the surrounding skull. These findings can support prompt tumor resection.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Calvarial angiomatous meningioma developed in the diploe

Sugiyama

Tsutsumi

Hashizume

et al. 2022

Surgical Neurology International

View full text Add to dashboard Cite

show abstract

“…Intraosseous neurofibroma is very rare and approximately one quarter of reported cases have been associated with neurofibromatosis 24 . Most reported cases have arisen in the mandible; however, other very rare sites of occurrence have been reported, including the frontal bone, tibia, femur, ulna, maxilla, clavicle, and vertebral body 24 . Neurofibromas contain a mixture of S100 and SOX10 positive Schwann cells, CD34 positive stromal fibroblasts, and a small number of EMA positive perineurial cells 25 .…”

Section: Discussionmentioning

confidence: 99%

“…We considered the possibility of an intraosseous nerve sheath tumor, more specifically neurofibroma. Intraosseous neurofibroma is very rare and approximately one quarter of reported cases have been associated with neurofibromatosis 24 . Most reported cases have arisen in the mandible; however, other very rare sites of occurrence have been reported, including the frontal bone, tibia, femur, ulna, maxilla, clavicle, and vertebral body 24 .…”

Section: Discussionmentioning

confidence: 99%

Spindle cell neoplasm with EML4‐ALK gene fusion presenting as an intraosseous vertebral mass

Mantilla

Cheung

et al. 2020

Genes Chromosomes & Cancer

View full text Add to dashboard Cite

In this article, we describe a spindle cell neoplasm harboring an EML4‐ALK gene fusion presenting as an intraosseous vertebral mass with extension into the adjacent soft tissue in a 65‐year‐old man. Histologically, the lesion was characterized by the presence of monotonous, cytologically bland spindle cells with loose myxoedematous stroma and interspersed areas of amianthoid‐like collagen fiber deposition. Immunohistochemistry demonstrated strong diffuse staining for CD34 and S100, with absent immunoreactivity for SOX10. At 1 year of follow‐up after resection, there is no evidence of local recurrence or metastatic disease. This case adds to the clinical and pathologic spectrum of the recently described group of kinase fusion‐positive spindle cell neoplasms and represents the first reported intra‐osseous example. The presence of ALK rearrangement in this lesion represents a potential therapeutic target, if clinically indicated.

show abstract

“…Hasta el momento, se han reportado menos de 40 casos (9). Con relación a los maxilares, se presenta con mayor frecuencia a nivel mandibular (10) y afecta, generalmente, el cuerpo y la rama de la mandíbula.…”

Section: Introductionunclassified

Diagnóstico de neurofibroma intraóseo solitario mandibular. Un reporte de caso

Forero–Herrera,

Amador–Preciado,

Fajardo-Ortiz

et al. 2023

Acta Odontol. Colomb.

View full text Add to dashboard Cite

Introducción: el neurofibroma es una neoplasia benigna de la vaina de los nervios periféricos, eventualmente asociada a la neurofibromatosis tipo I, también llamada enfermedad de Von Recklinghausen. Su presentación a nivel de cabeza y cuello es poco común, por lo cual existen pocos reportes. Objetivo: presentar un caso clínico con diagnóstico de neurofibroma intraóseo clínico y una revisión actualizada de la literatura. Una paciente de 46 años, tratada en un servicio de cirugía oral y maxilofacial de la ciudad de Bogotá, Colombia, con un diagnóstico de neurofibroma intraóseo solitario de tres meses de evolución, a quien se le descartó neurofibromatosis de Von Recklinghausen, el cual comprometía el cuerpo y la rama mandibular derecha. El diagnóstico se realizó utilizando imágenes diagnósticas, así como bloques y láminas para la revisión de la biopsia inicial y de la resección. Esto, con el fin de interpretar y realizar el diagnóstico histopatológico en el Servicio de Patología Oral y Maxilofacial de la Facultad de Odontología de la Universidad Nacional de Colombia (FOUN), donde se efectuaron cortes en coloración de hematoxilina y eosina y marcadores de inmunohistoquímica. Conclusión: el tratamiento realizado incluyó la resección quirúrgica de la lesión, injerto óseo y recubrimiento con membrana alogénica de dermis humana.

show abstract

Solitary Intraosseous Neurofibroma of the Frontal Bone -Case Report-

Cited by 6 publications

References 18 publications

Calvarial angiomatous meningioma developed in the diploe

Calvarial angiomatous meningioma developed in the diploe

Spindle cell neoplasm with EML4‐ALK gene fusion presenting as an intraosseous vertebral mass

Diagnóstico de neurofibroma intraóseo solitario mandibular. Un reporte de caso

Contact Info

Product

Resources

About