Solitary plasmacytoma and extramedullary plasmacytoma of the paranasal sinuses and soft palate

Abstract

Solitary plasmacytoma of the paranasal sinuses are uncommon neoplasms of B lymphocyte origin. They comprise one per cent of all head and neck tumours of the upper respiratory tract. They can be solitary plasmacytomas of the bone (SPB), an extramedullary plasmacytoma or a local manifestation of multiple myeloma. Conversion to multiple myeloma happens more frequently in SPB. Radiotherapy is the common modality of treatment with, or without, adjuvant chemotherapy. Extramedullary plasmacytoma carries a better prognosis than a solitary plasmacytoma of the bone. We report four cases of solitary plasmacytoma of the bone and an extramedullary plasmacytoma of the paranasal sinuses and soft palate.

Extended applications of endoscopic sinus surgery and its reference to cranial base and pituitary fossa

“…The diagnostic classification of plasma cell neoplastic disorders includes: Solitary plasmacytoma of bone commonly presents as single large osteolytic lesion, often with multicystic areas of rarefaction. Moreover, almost 50% of solitary plasmacytomas will convert to multiple myeloma [43]. It is essential to look for evidence of systemic involvement and the presence of paraprotein.…”

Multiple cystic swelling: Initial presentation of multiple myeloma

“…Few case reports are available about solitary plasmacytoma and extramedullary plasmacytoma of the paranasal sinuses and soft palate. [2] We are reporting a case of multiple myeloma in a 55-year-old male who presented with multiple cystic swellings on the chest. There is no case report available.…”

Extramedullary Plasmacytoma of Gingiva and Soft Tissue in Neck

“…Radiotherapy is the choice of treatment since plasmacytoma is very radiosensitive [16,17]. Some reports have shown long term control following radiotherapy in a solitary lesion with high likelihood of cure [3,18,19].…”