Solitary subungual neurofibroma in the right first finger

Abstract

Solitary subungual neurofibroma appears to be a rare condition, and immunohistochemistry is the key to the diagnosis. Complete surgical excision should be considered as the curative treatment of choice for them.

Solitary subungual neurofibroma with glomus tumor-like appearance: a case report

“…A clinical diagnosis of solitary subungual neurofibroma before histological examination of the tumor is difficult because it is rare and does not usually demonstrate pathognomonic symptoms [5]. The present patient was considered to be a case of glomus tumor because of the subungual preponderance of the tumor [6].…”

“…Three previously reported cases showed thickening and elevation of the nail plate [4,8,9], while nail dystrophy was reported in five cases [3,4,7,10], including the present case. Only one case had no nail plate deformity [5]. MRI findings of normal intensity in T1weighed image, high intensity in T2-weighed image and presence of intra-tumoral flow void were indicative of both neurofibroma and glomus tumor.…”

Multiple linear subcutaneous nodules

“…2 Though sporadic solitary neurofi broma can occur in any part of the body, it is commonly seen on the head and neck, and occasionally on the presacral and parasacral space, thigh, intrascrotal area, 3 the ankle and foot, 4,5 and the subungual region. 6 A series of 397 peripheral neural sheath tumors examined over 30 years showed 55 sporadic solitary neurofi bromas occurring in the brachial plexus region, 45 in the upper extremities, 10 in the pelvic plexus, and 31 in the lower extremities. 7 Management of sporadic solitary neurofi broma depends on the patient's discomfort.…”

The Importance of Preoperative Imaging Study on a Solitary Neurofibroma Originated from the Digital Nerve

“…Multiple neurofibromatosis is closely related to von Recklinghausen's disease which can be easily diagnosed by familial history along with physical examination 2 . On the other hand, solitary neurofibroma without any underlying disease is rare 1,2 . This is a case of solitary neurofibroma originating from a digital nerve located between third metacarpal bone and third proximal phalanx which was misdiagnosed as giant cell tumor, ganglion cyst, or fibroma originating from tendon prior to the histopathology result.…”

“…Neurofibroma is one form of neurofibromatosis which can occur in multiple or in a solitary nodule 1 . Multiple neurofibromatosis is closely related to von Recklinghausen's disease which can be easily diagnosed by familial history along with physical examination 2 .…”