Solubility and saturation apparent specific volume of some sodium sulfonamides in propylene glycol + water mixtures at 298.15 K

Muñoz, María M.; Rodríguez, Carlos J.; Delgado, Daniel Ricardo; Peña, María Ángeles; Jouyban, Abolghasem; Martínez, Fleming

doi:10.1016/j.molliq.2015.07.016

Cited by 14 publications

(2 citation statements)

References 22 publications

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“…Whether the process is endothermic or exothermic could be inferred by the enthalpy value of the mixing process in pure solvents. The Δ mix H value is negative, indicating that the dissolution process of ribavirin(II) is exothermic, and the forces between the solute and solvent molecules are mutually exclusive. , In addition, the dissolution process in other solvents is endothermic. The positive value of Δ mix S in all pure solvents indicates that the dissolution process is driven by entropy.…”

Section: Resultsmentioning

confidence: 99%

Measurement and Correlation of the Solubility and Thermodynamic Properties of Ribavirin(II) in Nine Pure Solvents and (1-Propanol + Water) Binary Solvents

Zhou

Zhang

et al. 2021

J. Chem. Eng. Data

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The solubility of ribavirin(II) in nine pure solvents (formic acid, dimethyl sulfoxide, water, methanol, ethanol, 1propanol, 1-butanol, 2-butanol, and acetone) and a 1-propanol−water binary system was analyzed by a gravimetric method under atmospheric pressure and temperature ranging from 283.15 to 323.15 K. Experimental results show that when the temperature increases, the fractional solubility in all selected solvents also increases, and the dissolution behavior is affected by the solvent polarity. The solubility of ribavirin(II) is correlated with the modified Apelblat equation, λh model, and nonrandom two-liquid (NRTL) model, indicating that these three models can satisfactorily predict the experimental values. The modified Apelblat equation shows better fitting performance than the other models. The NRTL model was also used to calculate the mixing thermodynamic properties of ribavirin(II) solution, including mixing Gibbs energy, mixing enthalpy, and mixing entropy. The results show that the dissolution of ribavirin(II) is a spontaneous and entropy-driven process.

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Section: Resultsmentioning

confidence: 99%

Measurement and Correlation of the Solubility and Thermodynamic Properties of Ribavirin(II) in Nine Pure Solvents and (1-Propanol + Water) Binary Solvents

Zhou

Zhang

et al. 2021

J. Chem. Eng. Data

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show abstract

“…Solubility and thermodynamic properties are important physicochemical parameters which are useful in crystallization, purification, formulation development, and preformulation studies. − The solubility data and thermodynamic properties of veramoss are unavailable in the literature and are needed to control the supersaturation, particle size, and desired polymorphic form in the crystallization process . Therefore, much more attention should be paid to the solubility and thermodynamic parameters of veramoss.…”

Section: Introductionmentioning

confidence: 99%

Solubility and Thermodynamic Behavior of Veramoss in Different Pure Solvents and {Ethanol + Water} Mixtures from T = 283.15 to 333.15 K

Chen

et al. 2016

J. Chem. Eng. Data

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The solubility of veramoss in n-butyl alcohol, ethanol, isopropanol, ethyl acetate, acetone, tetrahydrofuran, isoamyl alcohol, n-amyl alcohol, n-propyl alcohol, and DMF pure solvents and various {ethanol + water} mixtures at T = 283.15−333.15 K and atmospheric pressure was measured by using the dynamic method. The experiment solubility data showed that the solubility of veramoss increased with increasing temperature in all solvents selected and decreased with the rise of mole fraction of water in the binary solvent mixtures of {ethanol + water}. The modified van't Hoff equation and the Apelblat model were successfully used to correlate the experimental solubility in pure solvents while the modified Apelblat model, the van't Hoff equation, and the CNIBS/R model were applied to correlate the solubility in binary solvent mixtures, and all of the models provided good fitting to the data. Furthermore, the thermodynamic parameters (dissolving enthalpy, dissolving entropy, and Gibbs free energy) of veramoss in different solvents were also calculated based on the Wilson equation and experimental solubility data; the dissolving process of veramoss in all selected pure solvents was observed as an endothermic, nonspontaneous, and entropy-driven process and in the binary solvent mixtures of {ethanol + water} was observed as an endothermic, spontaneous, and entropy-driven process. The data of experimental solubility, correlation equations, and thermodynamic property can be used as essential data for a preliminary study of industrial applications.

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Modulation of biopharmaceutical properties of acidic drugs using cationic counterions: A critical analysis of FDA-approved pharmaceutical salts

Bharate

2021

International Journal of Pharmaceutics

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Solubility and saturation apparent specific volume of some sodium sulfonamides in propylene glycol + water mixtures at 298.15 K

Cited by 14 publications

References 22 publications

Measurement and Correlation of the Solubility and Thermodynamic Properties of Ribavirin(II) in Nine Pure Solvents and (1-Propanol + Water) Binary Solvents

Measurement and Correlation of the Solubility and Thermodynamic Properties of Ribavirin(II) in Nine Pure Solvents and (1-Propanol + Water) Binary Solvents

Solubility and Thermodynamic Behavior of Veramoss in Different Pure Solvents and {Ethanol + Water} Mixtures from T = 283.15 to 333.15 K

Modulation of biopharmaceutical properties of acidic drugs using cationic counterions: A critical analysis of FDA-approved pharmaceutical salts

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