Solubility of 2-(2,4,6-Trichlorophenoxy)ethyl Bromide in Methanol, Ethanol, Propanol, Isopropanol, Acetonitrile,<i>n</i>-Heptane, and Acetone

The solid–liquid solubility of indole-3-acetic acid in pure methanol, ethanol, n-propanol, isopropanol, acetone, n-butanol, acetonitrile, chloroform, ethyl acetate, 1,4-dioxane, N,N-dimethylformamide (DMF), and dimethyl sulfoxide (DMSO) was measured by using a isothermal saturation method. The determination temperature range is from 278.15 to 323.15 K. The order of solubility data from high to low was ethyl acetate > DMSO > DMF > n-butanol > acetone > isopropanol > 1,4-dioxane > n-propanol > ethanol > methanol > acetonitrile > chloroform. Two thermodynamic models (modified Apelblat equation and λh equation) were used to correlate the solubility values of indole-3-acetic acid in different monosolvents, and the two equations can correlate the experimental values very well. The values of root-mean-square deviations (RMSDs) and relative average deviations (RADs) between the experimental and calculated solubility values were not exceeding 0.27 × 10–6 and 0.75 × 10–2, respectively. In order to study the effect of solvation interaction on solubility, the solute–solvent and solvent–solvent interactions were discussed.

Section: Results and Discussionmentioning

confidence: 99%

Equilibrium Solubility, Model Correlation, and Solvent Effect of Indole-3-acetic Acid in Twelve Pure Solvents

Zhan

Chen

et al. 2019

“…The modified Apelblat equation − expressed in eq is a semiempirical model with three parameters. It has been widely used in describing the solubility of solute in pure solvents for binary solid–liquid phase equilibrium. In eq , x is the mole fraction solubility of sulfachloropyridazine in six organic solvents; A , B , and C are adjustable parameters in the modified Apelblat equation.…”

Section: Results and Discussionmentioning

confidence: 99%

Solubility of Sulfachloropyridazine in Pure and Binary Solvent Mixtures and Investigation of Intermolecular Interactions

Chen

et al. 2018

The solubility of sulfachloropyridazine in pure methanol, ethanol, isopropanol, 1-butanol, water, acetonitrile, ethyl acetate, acetone, 1,4-dioxane and (methanol + water), (ethanol + water), and (isopropanol + water) binary solvent mixtures was determined by using a isothermal saturation method with temperatures ranging from (283.15 to 323.15) K. The descending order of the solubility in pure solvents was as follows: 1,4-dioxane > acetone > acetonitrile > ethyl acetate > methanol > ethanol >1-butanol > isopropanol > water. In three mixed solvents, the solubility of sulfachloropyridazine increased with increasing temperature and mass fraction of alcohol. At the same mass fraction of methanol, ethanol, or isopropanol and temperature, the solubility of sulfachloropyridazine in (methanol + water) was greater than that in the other mixed solvents. The obtained solubility data were correlated with modified Apelblat equation and Jouyban−Acree model. The results of correlation showed good agreement with experimental data; the largest values of relative average deviations and the root-mean-square deviations between the experimental and calculated solubilities were 3.61 × 10 −2 and 6.37 × 10 −4 , respectively. Furthermore, molecular dynamics simulation was carried out to explain the dissolving ability of the model compound.

Section: Resultsmentioning

confidence: 99%

“…In the present work, the mole fraction solubility of sulfanilic acid in the studied solvents at corresponding temperatures was measured. The standard molar Gibbs energy of solution (Δ G soln 0 ) can be calculated according to where the intercept is determined in plots of ln x as a function of (1/ T ) (Figures and ). The standard molar entropy of solution (Δ S soln 0 ) is obtained by …”

Section: Results and Discussionmentioning

confidence: 99%

Thermodynamic Models for Determination of the Solubility of Sulfanilic Acid in Different Solvents at Temperatures from (278.15 to 328.15) K

Zhang

Shi³

et al. 2014

Self Cite

Data on corresponding solid−liquid equilibria of sulfanilic acid in different organic solvents are essential for industrial design and further theoretical studies. In this study, the solubilities of sulfanilic acid were measured in methanol, ethanol, 2-propanol, acetone, acetonitrile, formic acid, and acetic acid with the temperature range of (278.15 to 328.15) K by the analytical stirred-flask method under atmospheric pressure. For the temperature range investigated, the solubility of sulfanilic acid in the solvents increased with increasing temperature. The thermodynamic models, such as the van't Hoff model, the modified Apelblat model, and the Buchowski−Ksiazaczak λh model were investigated to describe the experimental data. It was found that the modified Apelblat model was the most suitable for predicting the solubility behavior of sulfanilic acid with increasing temperature. The calculated thermodynamic parameters indicated that in each studied solvent the dissolution process of sulfanilic acid is endothermic.