Solubility of citalopram hydrobromide in(ethanol + toluene) and (ethanol + ethyl acetate) at 283.15–318.15 K and its correlation with the Jouyban-Acree and CNIBS/R-K models

Wu, Yüfang; Wu, Jiaqin; Cheng, Long; Wang, Jiachao

doi:10.1016/j.fluid.2018.09.018

Cited by 9 publications

(3 citation statements)

References 11 publications

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“…Model correlation is important for the solubility data of solids. Many models have been reported to correlate or predict the solubility data of solids. − In this work, the 5-FC solubility data is correlated by the famous modified Apelblat model, , λ h model, Jouyban–Acree model, , and CNIBS/R-K model …”

Section: Resultsmentioning

confidence: 99%

“…The CNIBS/R-K model can also evaluate the solubility data in different solvent component mixtures and provides an accurate mathematical description of the solubility behavior at different temperatures When n = 2, the model form can be simplified as eq …”

Section: Resultsmentioning

confidence: 99%

“…25−27 In this work, the 5-FC solubility data is correlated by the famous modified Apelblat model, 28,29 λh model, 30 Jouyban−Acree model, 31,32 and CNIBS/R-K model. 33 The modified Apelblat model as a semiempirical model is suitable for polar and nonpolar systems that are established according to the principle of solid−liquid equilibrium by Apelblat. 28,29 The equation is described as eq 11.…”

Section: K Xs Xs Xs Xsmentioning

confidence: 99%

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Solubility of 5-Fluorocytosine in Different Pure and Binary Mixed Solvents: Measurement, Model Correlation, Solvent Effect, and Preferential Solvation

Cong

Wang

et al. 2021

J. Chem. Eng. Data

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In this work, the phase equilibrium solubility of 5-fluorocytosine (5-FC) in dimethyl sulfoxide (DMSO), N,N-dimethylformamide (DMF), 1-butanol, acetonitrile, 1-propanol, 1,4-dioxane, acetone, ethyl acetate, 2-propanol, 2-butanone, and mixture systems (DMSO + 2-propanol and DMF + 2-propanol) at a series of temperatures (283.15–323.15 K) is determined, and model correlation, solvent effect, and preferential solvation analysis are researched. The solubility of 5-FC is related to temperature, which decreases with decreasing temperature. For monosolvent systems, the mole solubility order is DMSO > DMF > 1-butanol > 1-propanol > 2-propanol > acetone > 2-butanone > 1,4-dioxane > acetonitrile > ethyl acetate. The solvent effect has been studied in monosolvents, hydrogen-bonding acceptor (HBA) interactions and nonspecific dipolarity/polarizability interactions favor dissolution, and solvent self-cohesiveness is not beneficial to dissolution. For two mixture systems, the mole solubility of 5-FC in DMSO + 2-propanol solvent systems is higher than that in DMF + 2-propanol solvent systems. A dimensionless parameter (δ) is defined to observe the deviation from ideality of mixed solvents whose values are all greater than zero. The equilibrium constant of the solvent exchange process (K ps) can be used to evaluate the preferential solvation of 5-FC. DMSO or DMF dissolves 5-FC in the local region around 5-FC preferentially. The equilibrium solubility data is correlated by four correlation models (modified Apelblat, λh, CNIBS/R-K, and Jouyban–Acree models). The greatest relative average deviation (RAD) and root-mean-square deviation (RMSD) values are 2.01% and 11.87 × 10–5 in pure solvent systems and 2.20% and 5.99 × 10–5 in mixture systems, respectively. These four models show excellent correlation with the experimental solubility data.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: K Xs Xs Xs Xsmentioning

confidence: 99%

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Solubility of 5-Fluorocytosine in Different Pure and Binary Mixed Solvents: Measurement, Model Correlation, Solvent Effect, and Preferential Solvation

Cong

Wang

et al. 2021

J. Chem. Eng. Data

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Solubility behaviour and thermodynamic analysis of methyleneaminoacetonitrile in binary (ethanol + water, ethanol + 2-propanol, ethanol + n-butanol) solvents

Wang

Sun

Hua

et al. 2019

The Journal of Chemical Thermodynamics

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Solubility and thermodynamic properties of piperine in (acetone/ethyl acetate + ethanol) at 278.15 K to 318.15 K and its correlation with the Jouyban-Acree and CNIBS/R-K models

Han

2021

The Journal of Chemical Thermodynamics

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Solubility of citalopram hydrobromide in(ethanol + toluene) and (ethanol + ethyl acetate) at 283.15–318.15 K and its correlation with the Jouyban-Acree and CNIBS/R-K models

Cited by 9 publications

References 11 publications

Solubility of 5-Fluorocytosine in Different Pure and Binary Mixed Solvents: Measurement, Model Correlation, Solvent Effect, and Preferential Solvation

Solubility of 5-Fluorocytosine in Different Pure and Binary Mixed Solvents: Measurement, Model Correlation, Solvent Effect, and Preferential Solvation

Solubility behaviour and thermodynamic analysis of methyleneaminoacetonitrile in binary (ethanol + water, ethanol + 2-propanol, ethanol + n-butanol) solvents

Solubility and thermodynamic properties of piperine in (acetone/ethyl acetate + ethanol) at 278.15 K to 318.15 K and its correlation with the Jouyban-Acree and CNIBS/R-K models

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Solubility of citalopram hydrobromide in(ethanol + toluene) and (ethanol + ethyl acetate) at 283.15–318.15 K and its correlation with the Jouyban-Acree and CNIBS/R-K models

Cited by 9 publications

References 11 publications

Solubility of 5-Fluorocytosine in Different Pure and Binary Mixed Solvents: Measurement, Model Correlation, Solvent Effect, and Preferential Solvation

Solubility of 5-Fluorocytosine in Different Pure and Binary Mixed Solvents: Measurement, Model Correlation, Solvent Effect, and Preferential Solvation

Solubility behaviour and thermodynamic analysis of methyleneaminoacetonitrile in binary (ethanol + water, ethanol + 2-propanol, ethanol + n-butanol) solvents

Solubility and thermodynamic properties of piperine in (acetone/ethyl acetate + ethanol) at 278.15 K to 318.15 K and its correlation with the Jouyban-Acree and CNIBS/R-K models

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Solubility behaviour and thermodynamic analysis of methyleneaminoacetonitrile in binary (ethanol + water, ethanol + 2-propanol, ethanol + n-butanol) solvents