Solubility of Genistein in Water, Methanol, Ethanol, Propan-2-ol, 1-Butanol, and Ethyl Acetate from (280 to 333) K

Abstract

The solubility of genistein in water, methanol, ethanol, propan-2-ol, 1-butanol, and ethyl acetate was measured at temperatures ranging from (280 to 333) K under atmospheric pressure using high-performance liquid chromatography (HPLC). Ethanol could be the most suitable solvent for purification and crystallization of geinstein. The experimental data were well-correlated with the Apelblat equation, which could be used as a useful model in the purification process of genistein.

A Process Synthesis Approach for Isolation of Isoflavones from Okara

“…35 However, a further analysis showed that one has to differentiate between the aglycones and glycosides, since their different natural structures, and therefore polarity and hydrophobicity, lead to their different extractive behavior. The aglycones have a much lower solubility in water than in ethanol, 16,36 and the cosolubilization of other components makes aqueous ethanol the preferred solvent. However, after the extraction of the isoflavones from okara, they have to be isolated from the extract.…”

Solubility of 1-Adamantanamine hydrochloride in Six Pure Solvents between 283.15 K and 333.15 K

“…pounds in different solvents played a crucial role in the determination of proper solvents and the development and operation of the crystallization process (Wu et al, 2010;Pankaj and Murthy, 2010).…”

Studies on the hydrogen bond acidity, and other descriptors and properties for hydroxyflavones and hydroxyisoflavones

“…The observed and fitted solubilities in the water-ethanol [24]. Solubilities have also been determined for genistein, 4′,5,7-trihydroxyisoflavone in a number of solvents by Wu et al [43] and by Nan et al [40], and a value for log P(oct) of 3.04 is available [42]. Unfortunately, the given solubilities in aprotic solvents are not compatible with either solubilities in alcohols or with the experimental value of log P(oct).…”