Solubility of sildenafil citrate in propylene glycol + water mixtures at various temperatures

Measurement and Correlation of the Solubility of Salbutamol in Ten Pure and Binary Mixed Organic Solvents from T = 283.15–328.15 K

“…In this model, van’t Hoff equation (eq ) and Jouyban–Acree equation (eq ) are combined to correlate the relationship among temperature, , solvent composition, and solubility. It can be described as eq . ln nobreak0em.25em⁡ x = x 2 .25em nobreak0em0.25em⁢ ln false( x 1 false) 2 + x 3 .25em ln ( x 1 ) 3 + x 2 x 3 ∑ i = 0 N J i ( x 2 − x 3 ) i T ln nobreak0em.25em⁡ x = x 2 .25em nobreak0em0.25em⁢ ln ( a 1 + b 1 T ) + x 3 .25em nobreak0em0.25em⁢ ln ( a 2 + b 2 …”

“…In this model, van’t Hoff equation (eq ) and Jouyban–Acree equation (eq ) are combined to correlate the relationship among temperature, , solvent composition, and solubility. It can be described as eq . where x 2 and x 3 are the molar composition of mixed solvent before adding solute; ( x 1 ) 2 and ( x 1 ) 3 are the solubility of solutes in 2-butanol and methanol; a 1 , b 1 , a 2 , and b 2 are derived from the van’t Hoff model fitting the solubility data of the solute in two pure solvents; N is the type of mixed solvent; T expresses the experimental temperature, J i is the model parameter, and in this system N = 2, x 3 = 1 – x 2 , this equation can be expressed as follows …”

“…van't Hoff−Jouyban−Acree Model. In this model, van't Hoff equation (eq 6) and Jouyban−Acree equation (eq 7) are combined to correlate the relationship among temperature, 18,19 solvent composition, and solubility. It can be described as eq 8.…”