Solubilization of Aqueous Solutions in Nonpolar Liquids

Abstract

— Water was solubilized in orange oil, soybean oil, benzyl alcohol, n‐heptane, n‐hexane and cottonseed oil. Using dioctyl sodium sulfosuccinate, aqueous ascorbic acid was solubilized in orange oil, soybean oil, benzyl alcohol, n‐heptane and n‐hexane. Triglycerol monooleate and decaglycerol dioleate, or caprylic acid and ethoxylated stearic acid solubilized aqueous ascorbic acid in cottonseed oil. Solubilization applications are suggested.

Pharmaceutical Sciences—1971: Literature Review of Pharmaceutics

“…A review of antacids included a discussion of factors to be considered in their evaluation (21 1). The solubilization of water-soluble materials, such as aqueous solutions of ascorbic acid, in nonpolar liquids by the use of appropriate surfactants was demonstrated by Morse et al (212). The manufacture and properties of pharmaceutical gelatins, as well as their numerous applications to pharmaceutical products, were extensively reviewed by Jones (213,214).…”