Solubilization of hydrophobic alcohols in aqueous Pluronic solutions: investigating the role of dehydration of the micellar core in tuning the restructuring and growth of Pluronic micelles

Patel, Vipul M.; Dey, Jahar; Ganguly, R.; Kumar, Sugam; Nath, Sukhendu; Aswal, Vinod K.; Bahadur, Pratap

doi:10.1039/c3sm50600b

Cited by 47 publications

(38 citation statements)

References 97 publications

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“…Addition of 1wt% hexanol resulted in a large increase in the scattering intensity at low Q. The linearity observed in the low Q region is suggestive of the ellipsoidal micelles [36,37]. Data fitting suggests the formation of prolate ellipsoidal micelles with major axis of 160 Å and a minor axis of 55 Å.…”

Section: Effect Of Alcohols On the Pluronic Micelle Structure Scattementioning

confidence: 78%

Probing competitive interactions in quaternary formulations

Mansour

Cattoz

Heenan

et al. 2015

Journal of Colloid and Interface Science

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Hypothesis: The interaction of amphiphilic block copolymers of the poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (PEO-PPO-PEO) group with small molecule surfactants may be "tuned" by the presence of selected alcohols, with strong interactions leading to substantial changes in (mixed) micelle morphology, whilst weaker interactions lead to coexisting micelle types. Experiments:The nature and the strength of the interactions between Pluronic P123 (EO20PO70EO20) and small molecule surfactants (anionic sodium dodecylsulfate, SDS, C12SO4Na), (cationic dodecyltrimethylammonium bromide, C12TAB) and (non-ionic polyoxyethylene(23)lauryl ether, Brij 35, C12EO23OH) is expected to depend on the partitioning of the short, medium and long chain alcohols (ethanol, hexanol and decanol respectively) and was probed using tensiometry, pulsed-gradient spin-echo nuclear magnetic resonance (PGSE-NMR) and small-angle neutron scattering (SANS). Findings:The SANS data for aqueous P123 solutions with added alcohols were well described by a charged spherical core/shell model for the micelle morphology. The addition of the surfactants led to significantly smaller, oblate elliptical mixed micelles in the absence of alcohols. Addition of ethanol to these systems led to a decrease in the 2 micelle size, whereas larger micelles were observed upon addition of the longer chain alcohols. NMR studies provided complementary estimates of the micelle composition, and the partitioning of the various components into the micelle.

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Section: Effect Of Alcohols On the Pluronic Micelle Structure Scattementioning

confidence: 78%

Probing competitive interactions in quaternary formulations

Mansour

Cattoz

Heenan

et al. 2015

Journal of Colloid and Interface Science

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“…As shown in Table , the density of decane increased by 8% with pressure increasing from 200 to 16 000 psi. The upturn at low q may correspond to either the presence of loose instantaneous clusters formed by micelles or to the elongation of spherical micelles into oblates or cylinders . Fitting the SANS data to a model for micelles of oblate or cylindrical shape showed no improvement over that of spherical micelles.…”

Section: Resultsmentioning

confidence: 93%

Polystyrene‐block‐Polyisoprene Diblock‐Copolymer Micelles: Coupled Pressure and Temperature Effects

Cheng

Hammouda

Perahia

2014

Macro Chemistry & Physics

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The structural changes of diblock‐copolymer micelles under pressures from 200 to 16 000 psi are investigated using small‐angle neutron scattering (SANS). Asymmetric polystyrene‐block‐polyisoprene (PS–PI) diblock copolymers are dissolved in decane, a selective solvent for PI, to form spherical micelles with a core of PS and a corona of PI. The micellar solutions are put under pressure at temperatures of 25 to 60 °C. At room temperature, elevating the pressure from 200 to 16 000 psi has no effect on the size of the micelles. While the micellar solutions remain stable, instantaneous association of micelles is detected. In contrast to micelles at atmospheric pressure, increasing the temperature at elevated pressures does not lead to dissociation of micelles; instead, the micelles aggregate and evolve into sheet‐like structures, reminiscent of a macroscopic phase separation. Furthermore, higher pressures lead to a smaller temperature range in which shape transitions take place.

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“…[13,14,15,16,17,18,35] Part of this interest stems from a desire to control the structure of block copolymer aggregates for templating mesoporous materials. [9,10] Stud-450 ies into solubilisation of oils by random copolymers are quite rare.…”

Section: Discussionmentioning

confidence: 99%

“…[10,13,14,18] SANS is a particularly powerful characterisation tool for 25 multi-component systems, given that deuterated chemicals are readily available. [19] By selectively deuterating different parts of a multi-component system, the polymer and solubilised domains can be discriminated, allowing a wealth of detailed structural information to be extracted from subsequent data analyses.…”

Section: Introductionmentioning

confidence: 99%

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Solubilisation of oils in aqueous solutions of a random cationic copolymer

Pegg

Czajka

Hazell

et al. 2017

Journal of Colloid and Interface Science

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General rightsThis document is made available in accordance with publisher policies. Please cite only the published version using the reference above. AbstractHypothesis. Reports of random copolymers capable of solubilising hydrophobic oils are rare. This is primarily because random copolymers are unlikely to self-assemble into suitable aggregates (or micelles) in water. A random copolymer with a "blocky" (or lumpy) microstructure may have potential to solubilise hydrophobic oils in water. This type of polymer would have advantages over block copolymers which are more laborious and costly to synthesise.Experiments. The solubilising capacity of a blocky random copolymer, namely poly(methyl methacrylate-co-2-dimethylaminoethyl methacrylate) (PMMA--co-PDMAEMA) is assessed by UV-visible spectroscopy and compared with common reference surfactants. The relative solubilising performance of random copolymers (across a narrow range of DMAEMA mol % fraction) for aromatic and aliphatic oils was also studied. The morphology of the aggregates was monitored as a function of the solubilisation capacity by small-angle neutron scattering (SANS) and dynamic-light scattering (DLS).Findings. Similarly to well-defined block copolymers, these random copolymers have a specific preference for solubilising aromatic over aliphatic oils. Increasing hydrophobicity of the copolymer enhances the solubilisation capacity. SANS has highlighted that aggregates become swollen and more uniform/spherical with increasing concentration of aromatic solubilisate, and that the aromatic solubilisate partitions throughout the random copolymer aggregates.

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Solubilization of hydrophobic alcohols in aqueous Pluronic solutions: investigating the role of dehydration of the micellar core in tuning the restructuring and growth of Pluronic micelles

Cited by 47 publications

References 97 publications

Probing competitive interactions in quaternary formulations

Probing competitive interactions in quaternary formulations

Polystyrene‐block‐Polyisoprene Diblock‐Copolymer Micelles: Coupled Pressure and Temperature Effects

Solubilisation of oils in aqueous solutions of a random cationic copolymer

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