Solution stability of Cu(II) metal–organic polyhedra

Vetromile, Carissa M.; Lozano, A. M.; Feola, Stephanie; Larsen, Randy W.

doi:10.1016/j.ica.2011.08.010

Cited by 26 publications

(22 citation statements)

References 34 publications

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“…Further the advantage of the chemical stability in addition to solubility in different media for given MOP cages favors their use in the biochemical environments. 9 The construction like capsules, boxes and polyhedral shapes with desired functions in a controlled manner is easily governed with the help of self-assembly principles. Large windows in the cages serve as the gateway passage for small molecules providing an opportunity to use them in the biophysical applications.…”

Section: Metal-organic Molecular Cagesmentioning

confidence: 99%

“…Therefore, MOPs have great potential in biochemistry owing to solution stability and properties under specific experimental conditions and chemical environments like acidic, basic, sensing species, and temperature etc. [7][8][9] Binding studies based on host-guest chemistry have dominated the field of molecular recognition. MOPs can play a role of molecular sensors due to their several significant features for example spatial selection resulting from cavity size, tuning the hydrophobicity incorporated hydrogen bond acceptor and donor sites, etc.…”

Section: Molecular Recognition and Imagingmentioning

confidence: 99%

“…The phenomena of selfassembling, resulting in the highest degree of symmetry from a multiple number of subunits, are frequently observed in biological systems, e.g., ferritin, capsid and tobacco mosaic utility of MOPs can be extended based on the features like permanent porosity, highly selective guest binding/encapsulation, solubility, chemical and thermal stability etc. 8,9 The use of hostguest chemical systems in catalysis and sorption based separations has been a popular subject. Recently, self-assemblies have attracted the attention for applications of the biochemical relevance.…”

Section: Introductionmentioning

confidence: 99%

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Metal–organic molecular cages: applications of biochemical implications

et al. 2015

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New well-designed materials are highly demanded with the prospect of versatile properties, offering successful applications as alternates to conventional materials. Major new insights into metal-organic self-assembled structures assisting biochemical purposes have recently emerged. Metal-organic polyhedral cages are highlighted as new research materials to be used for therapeutic, sensing and imaging, purposes etc. This tutorial review covers achievements in the biochemical applications of these multinuclear complexes. Examples of their ability to aid the ionic transport, biomolecular sensing, imaging, and drug delivery are presented.

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Section: Metal-organic Molecular Cagesmentioning

confidence: 99%

Section: Molecular Recognition and Imagingmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Metal–organic molecular cages: applications of biochemical implications

et al. 2015

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“…[60][61][62] However, this reversibility is also a source of concern when assessing their stability, because they can dissociate in the presence of competing coordinating molecules such as water (i.e., hydrolysis) or additional ligands (i.e., ligand exchange). [63,64] Therefore, strategies to augment the robustness of MOPs in solution focus on either shielding the metallic node, using metal ions with strong intermetallic bonds, increasing the coordination strength of the metal-ligand coordination bond, or using chelating groups (Figure 2).…”

Section: Stabilitymentioning

confidence: 99%

Metal–Organic Polyhedra as Building Blocks for Porous Extended Networks

et al. 2022

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Metal-organic polyhedra (MOPs) are a subclass of coordination cages that can adsorb and host species in solution and are permanently porous in solid-state. These characteristics, together with the recent development of their orthogonal surface chemistry and the assembly of more stable cages, have awakened the latent potential of MOPs to be used as building blocks for the synthesis of extended porous networks. This review article focuses on exploring the key developments that make the extension of MOPs possible, highlighting the most remarkable examples of MOP-based soft materials and crystalline extended frameworks. Finally, the article ventures to offer future perspectives on the exploitation of MOPs in fields that still remain ripe toward the use of such unorthodox molecular porous platforms.

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“…12,13 The majority of MOP reports focus on solid state structure [14][15][16] and much about MOP formation and solution state behavior remains unexplored. [17][18][19][20] First, nearly all MOPs utilize the paramagnetic copper(II) paddlewheel SBU that unfortunately renders NMR analyses, which offer powerful insight into the solution integrity and host-guest behavior of artificial molecular capsules, obtuse due to the hyperfine shift. 21 Second, carboxylate based MOPs are neutral and often poorly soluble.…”

mentioning

confidence: 99%