Solvatochromism of dyes inspired in Effenberger's probe

A highly selective probe engineered to detect polarity and distinguish normal cells and tumor cells in tissue sections

“…absorption band observed in spectrum for DCI-Cou-polar is due to a p-p* transition, of an intramolecular charge transfer nature, which occurs from the coumarin electron-donor group to the dicyanoisophorone electron-acceptor group. 43 As shown in Fig. 2B, the uorescence spectrum of the probe showed signicant solvatochromicity.…”

Ferrocene analogs of Brooker's merocyanine: a new library of organometallic inverted solvatochromic dyes

“…Purely organic solvatochromic dyes can be constructed by linking an electron donor and an electron acceptor group through a π-conjugated system. 1 Many chemical groups have been applied to this scheme (i.e., phenolates, 2 aminoaryls, [13][14][15] nitroaryls, 3,[16][17][18] and cationic azaheterocycles [19][20][21][22] ), giving rise to a collection of dyes displaying the three types of solvatochromism, but with a marked lack of examples of dyes exhibiting inverted solvatochromism. This arises from the scarcity of guidelines for attributing to a structure a particular solvatochromic tendency before its synthesis and spectroscopic study, which limits the development of novel and better sensors.…”