Solvent-free synthesis of aryl-14H-dibenzo[a,j]xanthenes and 1,8-dioxo-octahydro-xanthenes using silica sulfuric acid as catalyst

Microwave-assisted solvent-free synthesis of 14-aryl/alkyl-14H-dibenzo[a,j]xanthenes and tetrahydrobenzo[a]xanthen-11-ones catalyzed by nano silica phosphoric acid

“…These compounds have important biological and pharmaceutical activities such as antibacterial and anti-inflammatory ones 3 . The best procedure for synthesis of 14-aryl/alkyl-14H-dibenzo [a,j]xanthene is the mixing of 2-naphthol with aldehydes in the presence of a catalyst.…”

“…The best procedure for synthesis of 14-aryl/alkyl-14H-dibenzo [a,j]xanthene is the mixing of 2-naphthol with aldehydes in the presence of a catalyst. This procedure have been catalyzed with silica sulfuric acid 4,5 , Dowex-50W 6 , sulfamic acid 7 , HClO 4 -SiO 2 8 , cyanuric chloride 9 , BF 3 .SiO 2 10 and InCl 3 11 . Tetrahydrobenzo[a]xanthenes-11-ones as benzoxanthene derivatives could be synthesized via one pot condensation of 2-naphthol, aldehydes and 1,3-diketones in the presence of an acidic catalyst.…”

Antioxidant, Antimicrobial and Antiproliferative Activities of Synthesized 2,2,5,5-Tetramethyl-9-aryl-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-dione Derivatives

“…[19] Analytical data for synthesized 2,2,5,5-tetramethyl-9-aryl-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-diones are listed below. 6.88 (t, 1H, J5′6′ = 7.9 Hz, J4′5′ = 7.8 Hz, H-5′); 13 …”

“…A wide variety of methods for the preparation of the xanthenes have been reported. [6][7][8][9][10][11] Antioxidants are necessary to control degenerative reactions produced by reactive oxygen and nitrogen species. These species are involved in several ailments including cancer, heart diseases and Alzheimer's disease.…”

Calcium Chloride/HCl An Efficient Co-catalytic System For Synthesis Xanthene Under Microwave Condition

“…To suppress these drawbacks, the search of a new and efficient catalyst with high catalytic activity, short reaction time, recyclability, and simple reaction condition for the preparation of xanthenes under neutral mild and practical conditions is of key interest. An improvement in reaction procedure is made by reacting 2-naphthol with alkyl/aryl aldehydes employing various catalysts such as Bronsted acids, [25][26][27] solid supported reagent, [28,29] Metal salt, [30,31] Metal triflate, [32] I2 , [33] Phosphosulfonic acid, [34] trichloroisocyanuric acid, (TCCA), [35] Vanadatesulfuric acid, [36] HBF4-SiO2. [37] However, some these methods are suffer from one or more shortcomings like expensive and toxic catalyst, acidic condition, long reaction time, low yield, preparation of catalyst require in some cases, use of heavy and toxic metal.…”