Solvent-free Synthesis of polymethoxy and dichloro p-nitrophenyl hydrazones

Abstract

A solvent-free method for the synthesis of novel p-nitrophenyl hydrazones was successfully developed. The condensation of the p-nitrophenyl hydrazine with aromatic aldehydes through this mechanochemical technique furnished three products (3a-c) with moderate to high yield. The developed method is eco-friendly, efficient, simple, and convenient and indicated high reproducibility, short reaction time, catalyst-free, simple workup, and afforded pure and unsolvated products.