Solvothermal Synthesis of Functional Magnetic Nanoparticles for Biocatalyst

Abstract

A facile and simple one-step solvothermal method has been developed to synthesize polyethyleneimine (PEI)-modified magnetic nanoparticles. Characterization of morphology, surface charges, crystal structure, and magnetic property confirmed the efficiency of this facile synthesis route. Lipase immobilized on the PEI-modified magnetic nanoparticles was used to synthesize vitamin A palmitate from vitamin A acetate and palmitic acid. The reuse of immobilized lipase can be extended to eight times by removing water during esterification with a conversion rate above 80 % for 12 h.

Polyethylenimine: a very useful ionic polymer in the design of immobilized enzyme biocatalysts

“…199 Lipases have been immobilized on PEI-modified magnetic nanoparticles and used to produce vitamin A palmitate via esterification reactions. 200 Fe 3 O 4 magnetic nanoparticles were coated with PEI followed by grafting β-cyclodextrin and utilized to immobilize lipase utilized in the production of ethyl valerate. 201 Other enzymes have also been immobilized on PEI coated nanoparticles.…”