Somatosensory evoked potentials after median and tibial nerve stimulation in healthy newborns

Laureau, E; Marlot, D.

doi:10.1016/0013-4694(90)90098-5

Cited by 23 publications

(8 citation statements)

References 20 publications

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“…Our results are supported by those of Smit [29], who reported that preterm infants presented greater N1 peak latencies compared to full-term babies, both at TEA and at 6 months CA [11,13,30,31]. These findings could suggest that extrauterine maturation of the somatosensory pathway in very preterm newborns might be delayed compared to the maturation in full-term infants [11,13,30,31], possibly because of a delay in central myelination but also for the immature functioning of the synapses [32,33]. Conversely, two other studies did not confirm our results; both studies included infants of older GA with a greater birth weight (GA < 37 weeks and birth weight > 1500 gr), compared to our cohort [31,34].…”

Section: Seps: Preterm Vs Term Infantssupporting

confidence: 91%

Evaluation of the Relationship between Pain Exposure and Somatosensory Evoked Potentials in Preterm Infants: A Prospective Cohort Study

Coviello,

Lori,

Bertini

et al. 2024

Children

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Background and aim: First, to compare somatosensory evoked potentials (SEPs) in preterm newborns without major brain injury studied at term equivalent age (TEA) with a term historical control group. Second, to investigate the impact of pain exposure during the first 28 days after birth on SEPs. Third, to evaluate the association between SEPs and Bayley-III at 2 years corrected age (CA). Methods: Infants born at <32 weeks’ gestational age (GA) were studied with continuous-SEPs. First, SEP differences between preterm and term infants were analyzed. Second, regression analyses were conducted to explore the association between SEPs and painful procedures, and then between SEPs and neurodevelopment. Results: 86 preterm infants were prospectively enrolled. Preterm infants exhibited prolonged N1 latencies, central conduction times (CCTs), lower N1-P1 amplitudes, and more recurrently abnormal SEPs compared to term infants. Higher pain exposure predicted longer N1 latency and slower CCT (all p < 0.005), adjusting for clinical risk factors. Younger GA and postmenstrual age (PMA) at SEP recording were associated with longer N1 latency and lower N1-P1 amplitude (all p < 0.005). A normal SEP at TEA positively predicted cognitive outcome at 2 years CA (p < 0.005). Conclusion: Pain exposure and prematurity were risk factors for altered SEP parameters at TEA. SEPs predicted cognitive outcome.

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Section: Seps: Preterm Vs Term Infantssupporting

confidence: 91%

Evaluation of the Relationship between Pain Exposure and Somatosensory Evoked Potentials in Preterm Infants: A Prospective Cohort Study

Coviello,

Lori,

Bertini

et al. 2024

Children

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“…The detection rate of SEPs, even in healthy neonates, is dependent on the stimulation rate and filter settings, which significantly affect the SEP latencies and amplitudes . Studies using a stimulation rate of ≤2 Hz and a high‐pass filter ≤10 have reported a success rate of 100% for recording cortical SEPs in healthy neonates , whereas a stimulation rate of >2 Hz and a high‐pass filter of ≥20 yielded SEP success rates as low as 66%–87% .…”

Section: Discussionmentioning

confidence: 99%

Neonatal somatosensory evoked potentials persist during hypothermia

et al. 2017

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“…With increasing gestational age, the amplitude of this slow wave gradually decreases and an earlier component, usually referred to as N1 in the literature, becomes detectable with a latency of approximately 90 ms somewhere between the 27th (Taylor et al, 1996) and 29th GW (Hrbek et al, 1973). Toward term-age, the N1 latency rapidly decreases (Hrbek et al, 1973; Klimach and Cooke, 1988a; Karniski et al, 1992; Taylor et al, 1996; Smit et al, 2000), reaching approximately 30 ms at term-age (sep MN 30), though with considerable inter-individual variability (Desmedt and Manil, 1970; Hrbek et al, 1973; Laget et al, 1976; Zhu et al, 1987; Laureau et al, 1988; Laureau and Marlot, 1990; George and Taylor, 1991; Gibson et al, 1992; Karniski, 1992). …”

Section: Normal Development Of the Somatosensory Systemmentioning

confidence: 99%

Development of Human Somatosensory Cortical Functions â€“ What have We Learned from Magnetoencephalography: A Review

Nevalainen

Lauronen

Pihko

2014

Front. Hum. Neurosci.

107

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The mysteries of early development of cortical processing in humans have started to unravel with the help of new non-invasive brain research tools like multichannel magnetoencephalography (MEG). In this review, we evaluate, within a wider neuroscientific and clinical context, the value of MEG in studying normal and disturbed functional development of the human somatosensory system. The combination of excellent temporal resolution and good localization accuracy provided by MEG has, in the case of somatosensory studies, enabled the differentiation of activation patterns from the newborn’s primary (SI) and secondary somatosensory (SII) areas. Furthermore, MEG has shown that the functioning of both SI and SII in newborns has particular immature features in comparison with adults. In extremely preterm infants, the neonatal MEG response from SII also seems to potentially predict developmental outcome: those lacking SII responses at term show worse motor performance at age 2 years than those with normal SII responses at term. In older children with unilateral early brain lesions, bilateral alterations in somatosensory cortical activation detected in MEG imply that the impact of a localized insult may have an unexpectedly wide effect on cortical somatosensory networks. The achievements over the last decade show that MEG provides a unique approach for studying the development of the somatosensory system and its disturbances in childhood. MEG well complements other neuroimaging methods in studies of cortical processes in the developing brain.

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Somatosensory evoked potentials after median and tibial nerve stimulation in healthy newborns

Cited by 23 publications

References 20 publications

Evaluation of the Relationship between Pain Exposure and Somatosensory Evoked Potentials in Preterm Infants: A Prospective Cohort Study

Evaluation of the Relationship between Pain Exposure and Somatosensory Evoked Potentials in Preterm Infants: A Prospective Cohort Study

Neonatal somatosensory evoked potentials persist during hypothermia

Development of Human Somatosensory Cortical Functions â€“ What have We Learned from Magnetoencephalography: A Review

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