Somatosensory evoked potentials in Hirayama disease: A Brazilian study

Abstract

Background: Hirayama’s disease (HD) is characterized by an insidious onset asymmetric weakness and atrophy of the forearm and hand. Taking as a premise, the etiopathogenesis of the disease is attributed to forward displacement of posterior wall of lower cervical dural canal in neck flexion causing marked compression and flattening of lower spinal cord. This may result in compression of the posterior column of the spinal cord and seems likely to result in somatosensory evoked potentials (SSEPs) abnormalities. In the present study, we studied the possible involvement of the lemniscal dorsal pathway in patients with HD. Methods: SSEPs in upper and lower extremities were prospectively performed in eight patients with HD. All the patients were recruited from the outpatient clinic of a neuromuscular disorder center from South Brazil. SSEPs were obtained by transcutaneous electrical stimulation of the median and posterior tibial nerves, on both sides. We collected the amplitude and the latency of the different components obtained in each channel. The interpretation was based on Brazilian study standards. Results: We evaluated seven men and one woman (mean age 27). The data obtained were compared to a control group consisting of eight patients with spondylotic cervical myelopathy, 6 men and 2 women with mean age of 59 years. The measurements of obtained by the SSEP were also compared between the groups and no significant difference was found for any of them. Conclusion: SSEP did not turn out to be an electrophysiological marker in our HD patients.

[Retracted] Clinical Application of Evoked Potentials in the Operation of Cervical Spondylotic Myelopathy with Different Imaging

“…[13][14][15][16] In order to solve this problem, some scholars proposed to use somatosensory-evoked potential amplitude and latency to assess patients after spinal cord surgery to a The main basis for evaluating the effect of surgical treatment is that the amplitude of the evoked potential can determine the number of neurons in response to the stimulus (when the number of neurons in response to the stimulus decreases, the amplitude curve of the evoked potential decreases) and then determine the electrical conductivity of the injured neurons to the evoked potential when the spinal cord is compressed [20][21][22], which indirectly reflects the number of spinal cord nerve injuries in the patients. The literature shows that the level of SEP amplitude combined with morphological testing can more accurately determine the patient's injury and recovery [23][24][25].…”

Analysis of surgical treatment of cervical spondylotic amyotrophy

“…Diagnostic criteria: Patients with cervical spondylosis or previous history of cervical spondylosis, unilateral and a few bilateral upper limb amyotrophy, and the muscle strength of the affected limb has been weakened to a certain extent, without lower limb sensory disturbance; With or without upper limb root pain, sensory disturbance and positive pathological signs; Compression segment MRI T2WI weighted image with or without high signal of spinal cord; Neuroelectrophysiological examination was consistent with cervical spondylosis of amyotrophic type; Motor neuron disease, Hirayama disease and peripheral neuropathy (such as cubital tunnel syndrome) were excluded ( 12 ).…”

Somatosensory evoked potentials and Hirayama disease

“…presented a series of eight cases with HD for whom the SSEP test did not turn out to be an electrophysiologic marker. [ 1 ]…”