“…In this context, it is evident that most studies in this field have used young animals, but this makes it difficult to correctly standardize the model. 10,18,19,[22][23][24][25] References to the use of blood samples to measure musculoskeletal enzymes in rhesus monkeys cite various factors that can affect the viability of findings. These include age, sex, type of confinement, alimentation, state of health, and the effects of the different drugs that may be applied during chemical containment, as well as seasonal and geographic variations.…”