Somatostatin analog treatment of a cervical thoracic duct fistula

Valentine, Carl N.; Barresi, Roberto; Prinz, Richard A.

doi:10.1002/hed.10103

Cited by 57 publications

(38 citation statements)

References 16 publications

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“…However, in the present series. A systemic approach to decrease lymphatic output is the application of somatostatin analoga that has not been described in larger number of patients [27].…”

Section: Discussionmentioning

confidence: 99%

Management of lymph fistulas in thyroid surgery

Lorenz

Abuazab

Sekulla

et al. 2010

Langenbecks Arch Surg

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Data of this series support definition of the two categories of high- and low-output fistulas according to drainage collection with >300 versus <200 ml/day. Fasting in low-output fistula facilitates conservative treatment with closed drainage, whereas in high-output fistulas surgical intervention should be sought. Attendant criteria for treatment stratification are equally important, like patient's compliance, nutritional, and general health status as well as evidence for wound infection. Surgical closure of lymph fistula may be demanding when identification of the secreting fistula is limited and even muscle flap fortification may fail. Ultimately, in unsuccessfully reoperated fistula recurrences, open drainage may become necessary. Lymph fistulas cause significantly prolonged hospital stay, possible critical clinical decay, and unfavorable cosmetic and oncologic outcome while the superior management remains to be defined.

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“…However, in the present series. A systemic approach to decrease lymphatic output is the application of somatostatin analoga that has not been described in larger number of patients [27].…”

Section: Discussionmentioning

confidence: 99%

Management of lymph fistulas in thyroid surgery

Lorenz

Abuazab

Sekulla

et al. 2010

Langenbecks Arch Surg

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“…Conservative approaches to decreasing chyle production involve the placement of intercostal tube drainage for thoracentesis and absolute oral intake diet with total parenteral nutrition or an enteral diet rich in low-fat, medium-chain triglycerides [1,3,4]. Also, the use of somatostatin or octreotide has been used to decrease intestinal chyle production [5,6]. Unfortunately, conservative management is of low effi cacy in neoplasic chylothorax.…”

Section: Discussionmentioning

confidence: 99%

Chylothorax due to metastatic prostate carcinoma: an unusual complication

et al. 2009

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Chylothorax, the abnormal accumulation of lymphatic fluid within the pleural space, is an infrequent complication of tumours affecting the mediastinum. The development of chylothorax is extraordinary in association with prostate cancer, although it has been described before. Adequate treatment of malignant chylothorax comprises both a conservative approach, including dietary and hormonal manipulations, and mechanic intercostal drainage that have been demonstrated to be effective in the management of chylothorax of malignant origin. Radiation therapy has been used for the treatment of neoplasic chylothorax but with inconsistent results. We present a new case of chylothorax associated to prostate adenocarcinoma and review the existing evidence for its treatment.

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“…[4][5][6][7] Nutritional treatment leads to closure of the fistula in up to 80% of patients. 8 Many physicians consider first-line therapy to be bowel rest, parenteral nutrition, and chyle drainage.…”

Section: Discussionmentioning

confidence: 99%