Somatotopographic organization in the second somatosensory area of <i>M. fascicularis</i>

Robinson, Charles J.; Burton, Harold

doi:10.1002/cne.901920104

Cited by 263 publications

(175 citation statements)

References 50 publications

Supporting

Mentioning

157

Contrasting

Order By: Relevance

“…Robinson and Burton (1980a) reported that the SII region contains a single cutaneous region flanked by "complex zones" that required active movement to drive the neurons, although these zones are smaller than the anterior and posterior fields reported here. More recently, Burton et al (1995) reported, using tracers injected into areas 3b and 1, that the AP length of the SII region exceeds 7 mm and contains separate anterior and posterior body maps.…”

Section: Are These Separate Areas?contrasting

confidence: 58%

“…Figure 12 shows a map summarizing the SII hand region along with our estimates of the body parts represented in the adjacent cortex. The map is similar in size and location within the UBLS to the map of Robinson and Burton (1980a), whose map consisted of a single cortical area, and to the maps of Burton et al (1995) and Krubitzer et al (1995), whose maps consisted of two separate cortical areas.…”

Section: Are These Separate Areas?mentioning

confidence: 75%

“…1). Initially, Woolsey (1943) and Woolsey and Fairman (1946) reported that the macaque SII consists of a single area, and this was also reported in later studies (Friedman et al, 1980;Robinson and Burton, 1980a;Pons et al, 1988). However, Whitsel et al (1969), and more recently Burton et al (1995) and Krubitzer et al (1995), suggested that SII consists of two areas.…”

Section: Introductionmentioning

confidence: 92%

“…It has long been known that neurons in the SII region have a variety of RF sizes (Robinson and Burton, 1980a). Is this because the neurons studied came from different cortical fields?…”

Section: Rf Sizementioning

confidence: 99%

See 3 more Smart Citations

Receptive Field Properties of the Macaque Second Somatosensory Cortex: Evidence for Multiple Functional Representations

et al. 2004

View full text Add to dashboard Cite

The detailed functional organization of the macaque second somatosensory cortex (SII) is not well understood. Here we report the results of a study of the functional organization of the SII hand region that combines microelectrode mapping using hand-held stimuli with single-unit recordings using a motorized, computer-controlled tactile oriented bar. The data indicate that the SII hand region extends ϳ10 mm in the anteroposterior (AP) dimension, primarily within the upper bank of the lateral sulcus. Furthermore, we find evidence that this region consists of multiple functional fields, with a central field containing neurons that are driven well by cutaneous stimuli, flanked by an anterior field and a posterior field that each contain neurons that are driven well by proprioceptive stimuli and less well by cutaneous stimuli. The anterior field extends ϳ4 -5 mm AP, the central field extends ϳ3-4 mm, and the posterior field extends ϳ3 mm. Data from the motorized stimulator indicate that neurons in the central field are more responsive to oriented bars, more frequently exhibit orientation tuning, and have larger receptive fields than neurons in the anterior and posterior fields. We speculate that the three putative fields play different functional roles in tactile perception; the anterior and posterior fields process information that involves both proprioceptive and cutaneous input such as sensorimotor integration or stereognosis, whereas the central field processes primarily cutaneous information.

show abstract

Section: Are These Separate Areas?contrasting

confidence: 58%

Section: Are These Separate Areas?mentioning

confidence: 75%

Section: Introductionmentioning

confidence: 92%

“…It has long been known that neurons in the SII region have a variety of RF sizes (Robinson and Burton, 1980a). Is this because the neurons studied came from different cortical fields?…”

Section: Rf Sizementioning

confidence: 99%

See 2 more Smart Citations

Receptive Field Properties of the Macaque Second Somatosensory Cortex: Evidence for Multiple Functional Representations

et al. 2004

View full text Add to dashboard Cite

show abstract

“…The peak activation of the parietal operculum, including S2, was more posteriorly located than in most previously published PET studies of pain in which the stimuli have been induced in the arm (Talbot et al, 1991;Casey et al, 1994Casey et al, , 1996Coghill et al, 1994;Craig et al, 1996;Rainville et al, 1997). In single neuron recordings of S2, it has been shown that the foot area is located more posteriorly than the face area in these structures (Robinson and Burton, 1980b). Andersson and coworkers (Andersson et al, 1997) reported increased activity in anterior parts of S2 when painful stimulation of the hand was compared with painful stimulation of the foot.…”

Section: Discussionmentioning

confidence: 60%

A PET activation study of dynamic mechanical allodynia in patients with mononeuropathy

Petrović¹,

Ingvar²,

Stone‐Elander³

et al. 1999

Pain

152

View full text Add to dashboard Cite

The objective of this study was to investigate the central processing of dynamic mechanical allodynia in patients with mononeuropathy. Regional cerebral blood¯ow, as an indicator of neuronal activity, was measured with positron emission tomography. Paired comparisons were made between three different states; rest, allodynia during brushing the painful skin area, and brushing of the homologous contralateral area. Bilateral activations were observed in the primary somatosensory cortex (S1) and the secondary somatosensory cortex (S2) during allodynia compared to rest. The S1 activation contralateral to the site of the stimulus was more expressed during allodynia than during innocuous touch. Signi®cant activations of the contralateral posterior parietal cortex, the periaqueductal gray (PAG), the thalamus bilaterally and motor areas were also observed in the allodynic state compared to both non-allodynic states. In the anterior cingulate cortex (ACC) there was only a suggested activation when the allodynic state was compared with the non-allodynic states. In order to account for the individual variability in the intensity of allodynia and ongoing spontaneous pain, rCBF was regressed on the individually reported pain intensity, and signi®cant covariations were observed in the ACC and the right anterior insula. Signi®cantly decreased regional blood¯ow was observed bilaterally in the medial and lateral temporal lobe as well as in the occipital and posterior cingulate cortices when the allodynic state was compared to the non-painful conditions. This ®nding is consistent with previous studies suggesting attentional modulation and a central coping strategy for known and expected painful stimuli. Involvement of the medial pain system has previously been reported in patients with mononeuropathy during ongoing spontaneous pain. This study reveals a bilateral activation of the lateral pain system as well as involvement of the medial pain system during dynamic mechanical allodynia in patients with mononeuropathy. q 1999 International Association for the Study of Pain. Published by Elsevier Science B.V.

show abstract

Changes in glutamate immunoreactivity in the somatic sensory cortex of adult monkeys induced by nerve cuts

1996

View full text Add to dashboard Cite

Antibodies to glutamate (Glu) were used to study the effects of reduced afferent input on excitatory neurons in the somatic sensory cortex of adult monkeys. In each monkey, immunocytochemical staining was compared to thionin and cytochrome oxidase (CO) staining in adjacent sections. In the cervical spinal cord, dorsal column nuclei, ventroposterior thalamus, and primary somatic sensory cortex (SI), Glu immunoreactivity (Glu-ir) was analogous to that described in normal animals; regions with reduced or absent Glu-ir were never observed and no appreciable differences were noted between the experimental and normal side. There were also no differences in CO or thionin-stained sections from the affected hemisphere. In the insuloparietal operculum, sections in the hemisphere contralateral to the nerve cut showed that most cortical fields had a normal pattern of Glu-ir (pattern a), some exhibited a reduction of Glu-ir (pattern b), and that in the central portion of the upper bank of the central sulcus, which corresponds to the general location of the hand representation of the second somatic sensory cortex (SII), Glu-ir had virtually disappeared (pattern c). Adjacent sections processed for CO or stained with thionin showed that in the regions corresponding to those characterized by pattern c, CO was slightly decreased and that glial cells had increased in number. In the regions of SII characterized by pattern c, small intensely stained glial cells displayed Glu-ir. These findings indicate that Glu-ir is regulated by afferent activity and suggest that changes in Glu levels in neurons as well as in glial cells may trigger the biochemical processes underlying the functional and structural changes occurring during a slow phase of reorganizational plasticity in the cerebral cortex of adult monkeys.

show abstract

Somatotopographic organization in the second somatosensory area of M. fascicularis

Cited by 263 publications

References 50 publications

Receptive Field Properties of the Macaque Second Somatosensory Cortex: Evidence for Multiple Functional Representations

Receptive Field Properties of the Macaque Second Somatosensory Cortex: Evidence for Multiple Functional Representations

A PET activation study of dynamic mechanical allodynia in patients with mononeuropathy

Changes in glutamate immunoreactivity in the somatic sensory cortex of adult monkeys induced by nerve cuts

Contact Info

Product

Resources

About