Some Biochemical and Nutritional Aspects in Fat Chemistry

DeuelJr., H. J.; Greenberg, Samuel M.

doi:10.1007/978-3-7091-7175-2_1

Cited by 1 publication

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“…Linoleic and arachidonic acids have the greatest therapeutic effect in the EFA-deficiency syndrome, while linolenic acid is less effective (see Deuel & Greenberg, 1950 for references). Arachidonic acid can also be formed from dietary linoleic acid (Mead, Steinberg & Howton, 1953).…”

Section: Male Fertilitymentioning

confidence: 99%

Prostaglandin E2 Prevents Impairment of Fertility in Rats Fed a Diet Deficient in Essential Fatty Acids

Hafiez¹

1974

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Summary. Male and female rats were fed a diet deficient in essential fatty acids for 5 months, starting at weaning. Some of these animals received no other treatment, while others were given prostaglandin E2, methyl arachidonate or a regular diet (Purina Lab Chow). At 3 and 6 months of age, the experimental rats were mated with untreated animals. At 3 months, only seven of eleven males fed the fat-free diet alone were fertile, while all males in the other three groups were fertile. At 6 months, five of eleven males fed the fat-free diet alone, ten of eleven males fed the fat-free diet plus methyl arachidonate, and all rats treated with prostaglandin or fed the regular diet were fertile.At 3 months, the females in the group fed the fat-free diet alone had irregular oestrous cycles, a prolonged gestation period and a smaller litter size than those in the other groups. Treatment with PGE2 had a deleterious effect on lactation, the lactation efficiency index being 0\m=.\4 in this group compared to 0\m=.\8to 0\m=.\9in the remaining three groups.At 6 months, most females were fertile and normal numbers of corpora lutea and implantation sites were observed in all groups.Prostaglandin E2 was apparently as effective as methyl arachidonate in preventing the impairment of fertility in rats fed the fat-free diet. Arachidonic acid is the major precursor for biosynthesis of prostaglandins E2 and F2\ g=a\ .

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Section: Male Fertilitymentioning

confidence: 99%

Prostaglandin E2 Prevents Impairment of Fertility in Rats Fed a Diet Deficient in Essential Fatty Acids

Hafiez¹

1974

Reproduction

View full text Add to dashboard Cite

show abstract

Some Biochemical and Nutritional Aspects in Fat Chemistry

Cited by 1 publication

References 282 publications

Prostaglandin E2 Prevents Impairment of Fertility in Rats Fed a Diet Deficient in Essential Fatty Acids

Prostaglandin E2 Prevents Impairment of Fertility in Rats Fed a Diet Deficient in Essential Fatty Acids

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