Some characteristics of the antibodies involved in allergic skin reactions of the horse to biting insects

Morrow, A. N.; Quinn, Patrick; Baker, K. P.

doi:10.1016/0007-1935(87)90107-2

Cited by 8 publications

(7 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, MELLOR and MCCAIG (1974) reported that the withers is the most frequent landing and biting site, o n horses, for C.pulicuris, the species which they suggested as the most probable cause of sweet itch in England. That the reactions produced in both horses resulted from a hypersensitivity response to Culicoides allergen rather than the presence of vasoactive or toxic substances is suggested by the relatively small reaction produced following skin tests o n some clinically normal horses using whole body extracts of Culicoides (QUINN et al, 1983) and the failure of these extracts to elicit reactions in guinea pigs (MORROW et al, 1987).…”

Section: It Would Appear Frommentioning

confidence: 96%

See 1 more Smart Citation

Skin Lesions of Sweet Itch and the Distribution of Dermal Mast Cells in the Horse

Morrow

Baker

Quinn

1987

Journal of Veterinary Medicine, Series B

View full text Add to dashboard Cite

Summary Intradermal skin tests using insect allergens were carried out in different regions of two horses; a horse with sweet itch and a clinically normal horse. There was greater variation in the response at challenge sites on the horse with sweet itch than on the normal horse. Mast cell counts were performed on skin samples taken from a number of regions of seven horses. While these cells tended to be more numerous along the dorsal mid‐line no clear pattern emerged which could be associated with the distribution of lesions in sweet itch. Mast cells tended to be more numerous in horses less than one year old. Zusammenfassung Hautläsionen bei Sommer‐Dermatitis und die Verteilung dermaler Mastzellen beim Pferd Intradermale Hauttests mit Insektenallergenen wurden an verschiedenen Hautregionen von 2 Pferden durchgeführt, bei einem Tier mit Sommer‐Dermatitis und einem klinisch gesunden Tier. Es waren größere Unterschiede in der Hautreaktion an den Teststellen bei dem Tier mit Sommer‐Dermatitis verglichen mit dem gesunden Tier festzustellen. Bestimmungen der Zahl der Mastzellen wurden anhand von Hautproben von verschiedenen Hautarealen bei 7 Pferden vorgenommen. Obwohl diese Zellart häufiger entlang der dorsalen Mittellinie vorzukommen scheint, war kein deutliches Verteilungsmuster in Verbindung mit dem Auftreten der Läsionen bei der Sommer‐Dermatitis festzustellen. Mastzellen waren bei Pferden im Alter unter 1 Jahr zahlreicher anzutreffen.

show abstract

Section: It Would Appear Frommentioning

confidence: 96%

“…Previous reports have shown the occurrence of immediate type hypersensitivity reactions to intradermal challenge with whole-body extracts of Crlicoides in horses with sweet itch (QUINN et al, 1983;MORROW et al, 1987).…”

Section: Introductionmentioning

confidence: 99%

Skin Lesions of Sweet Itch and the Distribution of Dermal Mast Cells in the Horse

Morrow

Baker

Quinn

1987

Journal of Veterinary Medicine, Series B

View full text Add to dashboard Cite

show abstract

“…It has been demonstrated in affected horses using intradermal injections of crude extracts of different Culicoides species (Riek 1954, Braverman et a/ 1983, Quinn, Baker, and Morrow 1983, Fadok and Greiner 1990. The presence of skin sensitising antibody in the serum of affected horses has been established using the Prausnitz-Kustner test (Riek 1954;Matthews, Imlah, and McPherson 1983;@inn et a/ 1983) and further analysis has revealed similarities to human IgE (Matthews et a1 1983;Morrow, Quinn and Baker 1987). Horses have shown clinical improvement on allergen specific immunotherapy for other conditions involving 3 p e I hypersensitivity mechanisms, such as chronic obstructive pulmonary disease (Halliwell et a/ 1979).…”

Section: Introductionmentioning

confidence: 99%

Specific immunotherapy in the treatment of Culicoides hypersensitive horses: A double‐blind study

Barbet

Bevier

Greiner

1990

Equine Veterinary Journal

View full text Add to dashboard Cite

Summary Fourteen privately owned horses completed a six month, controlled, double‐blind trial to assess the efficacy of immunotherapy using an aqueous extract of whole, unfed Culicoides variipennis in the treatment of Culicoides hypersensitivity. Selected horses had a history of a seasonal, pruritic dermatitis, clinical signs and distribution compatible with Culicoides hypersensitivity, failed to improve in response to ivermectin therapy, and reacted to several dilutions of Culicoides extracts without significant reactivity to other possible allergens including insects, moulds and feeds. One horse from the control group (n=8) and one from the test group (n=6) improved. Statistically, there was no significant difference between horses on Culicoides antigen and control horses. In each group, four owners thought that their horses had improved.

show abstract

“…The most important of the ectoparasites are thought to be midges as they can cause a pruritic dermatitis, known as sweet itch (Morrow et al 1987;Stevens et al 1988) and more club members had contacted their veterinary surgeons about this condition than for other ectoparasites. The greater importance of sweet itch reported in older horses in this survey is compatible with the development of an allergic response due to being repeatedly exposed to midge bites.…”

Section: Discussionmentioning

confidence: 99%

Parasite control in horses of members of pony clubs

Biggin¹,

Bristol²,

Coles³

1999

Equine Veterinary Education

View full text Add to dashboard Cite

Some characteristics of the antibodies involved in allergic skin reactions of the horse to biting insects

Cited by 8 publications

References 22 publications

Skin Lesions of Sweet Itch and the Distribution of Dermal Mast Cells in the Horse

Skin Lesions of Sweet Itch and the Distribution of Dermal Mast Cells in the Horse

Specific immunotherapy in the treatment of Culicoides hypersensitive horses: A double‐blind study

Parasite control in horses of members of pony clubs

Contact Info

Product

Resources

About