Some circulatory effects of morphine-barbiturate anesthesia, artificial respiration, and abdominal compression based on ballistocardiographic observations on dogs

Scarborough, William R.

doi:10.1016/0002-8703(57)90420-9

Cited by 14 publications

(4 citation statements)

References 79 publications

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“…Generally speaking the smaller the animal the more difficult it is to construct a ballistocardiograph capable of yielding a satisfactory record; animal experiments nearly always necessitate ansesthesia, and this itself may affect the circulation and grossly alter the ballistocardiogram (Scarborough, 1957); the circulation is such a closely integrated system that most manmuvres designed to alter it in any way are followed by a number of secondary adjustments which may well obscure the response of the ballistocardiogram to the initial interference. Much of the work in this field has therefore been disappointingly inconclusive though repeated observations have been made, which are consistent with the view that it is movement of the blood in the systemic arterial system that produces most of the ballistocardiographic signal and that stroke volume, peripheral resistance and, above all, peak accelerations of blood in the aorta are the important factors determining the amplitude and pattern of the record.…”

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confidence: 99%

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Ballistocardiography.

Deuchar¹

1967

Heart

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confidence: 99%

“…Early reports from the Johns Hopkins team (Scarborough et al, 1952) showed a much greater incidence of ballistocardiographic abnormality in a large group of patients with known coronary artery disease than in a similar group of apparently healthy people. This difference was particularly obvious below the age of 50 years.…”

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confidence: 99%

Ballistocardiography.

Deuchar¹

1967

Heart

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“…Using the dilution technique, the changes in resistance have ranged from -15 to +20% (Nahas, Visscher, Mather, Haddy, and Warner, 1954). The anaesthesia could also have played a significant role in producing changes in cardiac output, regional blood distribution, and venous return (Scarborough, 1957).…”

Section: Resultsmentioning

confidence: 99%

Treatment of experimental pulmonary embolism by main pulmonary arterial infusion of a fibrinolytic agent

Magtira¹,

Wells²,

Llamas³

et al. 1969

Thorax

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The continuous instillation of plasmin (Thrombolysin) directly into the main pulmonary artery of greyhounds, using one half of the systemic doses, was found to be more effective in accelerating or enhancing in vivo lysis of artificially produced pulmonary emboli than systemic intravenous infusion. Animals which received direct pulmonary arterial instillations of Thrombolysin showed remarkably few macroemboli. By light microscopy, these clots showed zones of lysis mainly in the central portions of the clots. We suggest that the flow-guided catheterization of the main pulmonary artery used in this study on greyhounds can be applied to critically ill human subjects, as shown by earlier studies (Magtira, Winkler, Duprey, and Baum, 1966). Continuous infusions of thrombolytic agents directly into the main pulmonary artery might then offer an effective therapy for human pulmonary embolism, especially during that critical period following a massive or sUbmassive embolic episode.

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“…An anesthetic agent such as sodium pentobarbital, which in addition may cause vasodilatation, would be expected to elicit an increase in ACR also as a consequence of a decrease in central blood voluine (88).…”

Section: Xi1 Interpretationsmentioning

confidence: 99%

Activity of Abdominal Muscles Elicited From the Circulatory System

Murphy

et al. 1963

American Journal of Physical Medicine & Rehabilitation

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The studies described in this paper deal with alterations in activity of abdominal inuscles and other slteletal inuscles which are elicited by changes in the cardiovascular system. A paper describing the initial studies was published in 1959 (45). Subsequent investigations have been described in Ph.D. theses by J. I<. Turner (94), L. D. Davis (as), D. I. Briggs (15), and A. S. Hoyc (57). Preliminary reports have been presented at meetings of the American Physiological Society and the American Heart Association (16, 30, 31, 44, 96, 99, 100). It seems appropriate to describe all of the studies in a single publication since they are concerned with the same basic problem, and the results are complementary in indicating that the activity of abdominal inuscles is increased selectively on a reflex basis when volume of blood in certain "low pressure" portions of the cardiovascular system, most probably thc left atrium, is reduced.

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Some circulatory effects of morphine-barbiturate anesthesia, artificial respiration, and abdominal compression based on ballistocardiographic observations on dogs

Cited by 14 publications

References 79 publications

Ballistocardiography.

Ballistocardiography.

Treatment of experimental pulmonary embolism by main pulmonary arterial infusion of a fibrinolytic agent

Activity of Abdominal Muscles Elicited From the Circulatory System

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