Some Epidemiological Aspects of Bronchial Asthma in Children in Qena Governorate, Egypt

Ka, Abdel-Baseer; Eem, Hammad; Qubaisy, Heba M.; Maaa, Naser; Aa, Ahmed; Am, Said

doi:10.4172/1745-7580.1000138

Cited by 4 publications

(4 citation statements)

References 30 publications

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“…4 In Egypt, the prevalence of asthma among school children in the Nile Delta region is about 7.7% 5 with probably underdiagnosis and undertreatment, particularly among children from less wealthy families. 6 Other studies reported an incidence of 9.4% in 11-15-year-old adolescents. 7 All these figures highlight the importance of setting a standardised approach in the management of children with chronic asthma with good interaction between healthcare providers and patients.…”

Section: Introduction and Scopementioning

confidence: 95%

“…It mainly occurs in young children and has an 8%–28% incidence and prevalence globally, and it is increasing yearly 4 . In Egypt, the prevalence of asthma among school children in the Nile Delta region is about 7.7% 5 with probably underdiagnosis and undertreatment, particularly among children from less wealthy families 6 . Other studies reported an incidence of 9.4% in 11–15‐year‐old adolescents 7 .…”

Section: Introduction and Scopementioning

confidence: 99%

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A protocol for adapting a clinical practice guideline for the treatment of paediatric asthma for the Egyptian Pediatric Clinical Practice Guidelines Committee

Abdel Baky,

Youssef,

Elsholkamy

et al. 2024

Clinical and Public Health Guidelines

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IntroductionPaediatric asthma is a prevalent and chronic respiratory condition affecting children worldwide. This protocol outlines the methodology for developing a clinical practice guideline (CPG) for the management of paediatric asthma. The goal of this guideline is to provide evidence‐based recommendations for healthcare professionals, improving the quality of care and health outcomes for paediatric patients with asthma.MethodsWe will use the ‘Adapted ADAPTE’ adaption method, a systematic approach to adapt existing guidelines, which consists of three phases (setup, adaptation and finalisation phases), nine modules and 24 steps, with adaptations to the process and tools to suit the Egypt healthcare context and resources.QuestionsClinical questions were prepared using the patient population, interventions, professionals, outcomes and healthcare context (PIPOH) model. This CPG protocol addresses critical clinical questions at the heart of effective asthma management in children. It focuses on the diagnosis of paediatric asthma, considering age‐specific clinical presentations and diagnostic tests, assessment of asthma severity, control medications like inhaled corticosteroids, long‐acting β‐agonists and others, with an emphasis on appropriate tools and criteria. The CPG also delves into the realm of long‐term control treatment, exploring the effectiveness and safety of pharmacological and nonpharmacological interventions, while considering individualised needs. Furthermore, it examines strategies for monitoring and adjusting treatment plans over time, ensuring optimal care. These clinical questions form the foundation of the CPG, facilitating evidence‐based care delivery and enhancing health outcomes for paediatric asthma patients.

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Section: Introduction and Scopementioning

confidence: 95%

Section: Introduction and Scopementioning

confidence: 99%

A protocol for adapting a clinical practice guideline for the treatment of paediatric asthma for the Egyptian Pediatric Clinical Practice Guidelines Committee

Abdel Baky,

Youssef,

Elsholkamy

et al. 2024

Clinical and Public Health Guidelines

View full text Add to dashboard Cite

show abstract

“…As a result, this causes the release of prostaglandin, leukotriene, and histamine. The occurrence of these events is cascaded by the continued proliferation and differentiation of B and T cells perpetuated by the release of cytokine, which eventually leads to frequently repeated coughing accounting for 70 to 80% prevalence of asthma in children { (Reinehr et al, 2018); (Baseer KA et al, 2017)}. Furthermore, the coughing also emanates from the continued subsequent inflammation and mucus production, which causes airway obstruction due to bronchoconstriction, thus impairing gas exchange (Holgate, 2008).…”

Section: Introductionmentioning

confidence: 99%

Efficacy and Safety of Aminophylline Versus Doxofylline in the Treatment of Bronchial Asthma: Systematic Review and Meta-Analysis

Allesburg¹

2023

Preprint

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Background: Bronchial asthma is a non-communicable disease that is highly prevalent globally, and the incidences of this drug increase daily with the increased environmental pollution. The most common interventional treatment for asthma includes methylxanthines, mainly doxofylline and aminophylline (ethylenediamine salt of theophylline). This study compared the efficacy of these two methylxanthines in treating bronchial asthma. Methodology: A literature search was performed through PubMed, MEDLINE, Google Scholar, and Cochrane. The Cochrane RevMan 5.4 software was used to perform a meta-analysis for the included studies.Results: Ten studies were included based on the satisfaction of the eligibility criteria. From the analysis, the spirometric values of FEV1, PEFR, FVC, and FEV/FVC demonstrated a statistically significant change/improvement from the baseline when using both aminophylline and doxofylline in the treatment of bronchial asthma. There was significant difference in mean FEV1 and FVC between the two drugs of (MD -0.02, 95% CI -0.03 to -0.01; P = 0.01) and (MD 0.02, 95% CI 0.01 to 0.04; P = 0.009), respectively. However, FEV1/FVC was not significant between aminophylline and doxofylline (MD 0.15, 95% CI -0.34 to 0.64; P = 0.55). Safety assessment between the two drugs shows significant differences with the use of both aminophylline and doxofylline OR 2.26, 95% CI 1.72 to 2.98; P < 0.00001). The heterogeneity across different analyses was high.Conclusion: The current study concluded that both doxofylline and aminophylline significantly improved the baseline conditions and functions of the lungs during the treatment of bronchial asthma. Doxofylline was superior to aminophylline in its efficacy and was also associated with lower incidences of adverse events and complications compared to aminophylline.

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“…Bronchial asthma is widespread in Egypt, and Children from poor socioeconomic categories are more likely to have undiagnosed or untreated bronchial asthma [6] . In Egypt, asthma prevalence was reported to be 7.7% in children less than 15 years old [7] .…”

Section: Introductionmentioning

confidence: 99%

Predictors of Asthmatic Children's Quality of Life in Damietta Governorate, Egypt

Yousef

Imam

Mahmmoud

et al. 2021

International Journal of Medical Arts

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Background: Bronchial asthma is the most prevalent illness among children and teenagers. It is considered a major cause of morbidity. The physical, social, and psychological domains of childhood asthma are all affected. Aim of the work:To measure the pediatric asthma quality of life [PAQOL] levels within asthmatic children and its main predictors in Damietta, Egypt.Methods: An analytical cross-sectional survey was carried out utilizing a questionnaire that assesses [PAQOL] levels with related socio-demographic factors and asthma control levels. Asthma control level was tested by an asthma control test questionnaire. PAQLQ as a dependent variable and other plausible independent variables were analyzed by a stepwise linear regression model. Results: Two hundred participants, aged 7-17 years were included; [56%] were females, [30.5%] residing in urban areas, and [77%] had belonged to middle and low socioeconomic classes. Gastro-esophageal reflux [GER] was shown to have a significant positive correlation with allergic rhinitis [P< 0.01] and obesity [P< 0.01]. Otherwise, GER was shown to be negatively correlated with asthma control status [P< 0.01]. Mean ± standard deviation [SD] of overall, activity and Emotion domains scores of QOL were 4.51± 1.3, 4.52± 1.25, and 4.54± 1.39 respectively. While more than 50% of the symptoms domain scores were more than 4.7. Low socioeconomic level [P< 0.01], poor asthma control [P< 0.01], and positive history for controller medications [P< 0.05] were significant predictors for lower asthmatic children's quality of life. Conclusion:Asthmatic children tend to have a poorer quality of life. To provide effective asthma treatment to the general public, prescribers and patients must both understand and be educated. Healthcare providers should consider PAQOL with greater attention to children with poor socio-economic standards and uncontrolled asthma in the management plan.

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Some Epidemiological Aspects of Bronchial Asthma in Children in Qena Governorate, Egypt

Abstract: Background: Bronchial asthma is one of the most prevalent diseases affecting children in both developed and developing countries. Due to paucity of data, we believe that epidemiological state of asthma should be wellestimated.

Cited by 4 publications

References 30 publications

A protocol for adapting a clinical practice guideline for the treatment of paediatric asthma for the Egyptian Pediatric Clinical Practice Guidelines Committee

A protocol for adapting a clinical practice guideline for the treatment of paediatric asthma for the Egyptian Pediatric Clinical Practice Guidelines Committee

Efficacy and Safety of Aminophylline Versus Doxofylline in the Treatment of Bronchial Asthma: Systematic Review and Meta-Analysis

Predictors of Asthmatic Children's Quality of Life in Damietta Governorate, Egypt

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