Some Immunological and Histopathological Changes for Frequently Aborted Women with Toxoplasmosis Infection

Abstract

The investigation comprised physiological and histological exams of 70 women with Toxoplasmosis and 30 women who were not affected. Samples from 20 placentas were obtained from groups, as well as blood and physiological examinations. The findings of the current investigation displayed a fundamental increase in concentration of IP-10(133.5 ± 120) and MCP (220.9 ± 122) in blood serum of patients suffering from Toxoplasmosis infection and control group IP-10 (94.8 ± 82) and MCP (199.7 ± 76). There were histological changes in the placenta tissue in aborted women due to the rapid reproduction of the parasite, and large spaces in the tissue due to the parasite's formation of tissue bags, which resulted in the death of cells forming the placenta tissue due to the parasite's secretions and toxic substances. Abortion or congenital deformities in the pregnancy, as well as impairments to the newborn neurological system.

Effect of Toxoplasma gondii infection on the level of NLRP3 in women with Polycystic Ovary Syndrome

“…As age advances, the quantity of eggs left in the ovaries reduces, and so does hormone output. The value of the analysis also increases in women who suffer from polycystic ovary syndrome due to the increase in the number of small follicles, which is less than 8 mm in the ovaries [19].…”