“…They, therefore, exploit an active diaphragm during expiration, in addition to laryngeal braking of flow and a high respiratory rate, to maintain end-expiratory lung volume (EELV) (2). With landmark observations in 1968 of grunting neonates at risk for alveolar derecruitment due to classic hyaline membrane disease (3), pioneers in this field soon realized the clinical importance of maintaining EELV in respiratory disease states for patients of all ages, leading toward first applications of continuous positive airway pressure (CPAP) and positive end-expiratory pressure (PEEP) during mechanical ventilation (4, 5).…”