The air temperature anomaly was analysed in 16 consecutive winters from 2004 to 2019 in southern Brazil using reanalysis data and hourly atmospheric observations. In this study, 13 heat wave (HW) episodes were identified using the percentile methodology. All identified episodes are associated with the occurrence of a downslope windstorm known as Vento Norte (VNOR; Portuguese for ‘North Wind’). The VNOR is characterized by a sharp increase in air temperature combined with constant, strong, gusty winds from the north and a drop in relative humidity. The average duration was about 5 days for HW and 18 h for VNOR being than in 59.5% of the HW hours, the VNOR windstorm was also detected. The main atmospheric variables were compared during the periods of winter, HW and the VNOR windstorm. The analysis showed that HW alters local weather and climate conditions, with the more pronounced features associated with the VNOR flow. A more detailed investigation comparing the atmospheric variables collected north and south of an abrupt change in terrain altitude (400 m) revealed that the main cause of the amplification of the atmospheric variable anomalies in the centre of the state of Rio Grande do Sul was the simultaneous occurrence of HW and VNOR.