Some Metal Ions Complexes Derived From Schiff Base Ligand with Anthranillic Acid: Preparation, Spectroscopic and Biological Studies

Abstract

This search includes the preparation of Schiff base ligand (SB) from condensation primary amine with vanillin. The new ligand was diagnosed by spectroscopic methods as Mass, NMR, CHN and FTIR. Ligand complexes were mixed from new (SB) and Anthranillic acid (A) with five metal (II) chlorides. The preparation and diagnosis were conducted by FTIR, CHN, UV-visible, molar conductivity, atomic absorption and magnetic moment. The octahedral geometrical shape of the complexes was proposed. The ligands and their new complexes were screened with two different types of bacteria.

Syntheses, Structures and Biological Activity of Some Schiff Base Metal Complexes

“…FT-IR spectra of compounds 1-4 are in agreement with free ligand spectrum Figs. (1)(2)(3)(4). Azomethine (C=N) group of the complexes 1-4 is noticed between 1615-1620 cm −1 confirming ligand synthesis successfully 18 .…”

“…Over decades Schiff base continue attracts antibiotic designer's attention because of distinctive chelating features 1 . Antibacterial activity of such ligand containing donor atoms can be enhanced significantly by coordination to a metal ion 2,3,4 . Moreover, some natural molecules such as chlorophyll, hemoglobin, carbonic anhydrase, vitamin B12, xanthine oxides, and hemocyanin clearly indicate the important linkage between organic ligand and metal elements 5 .…”

Mixed ligand complex: Synthesis, characterization, and investigation of biomedical activity

“…The Mohr technique was used to determine the chloride concentration in the complexes. Bruker 400 MHz NMR spectrometer was used to measure 1 H-NMR spectroscopy in d-DMSO 6 .…”

“…It has been proved clearly that new chemical ligands show improvement as physiologically active 5 . One type of ligand in the compound increases the chances of variation in the expected properties of the compound 6 .…”

Preparation, Characterization, Antioxidant and Antibacterial Studies of New Metal (II) Complexes with Schiff Base for 3-amino-1-phenyl-2- pyrazoline-5-one

“…3,4 The carbonyl group of the aldehyde gives aldimines while that of Ketone gives ketoimines, 5 and these provide binding site for the metal ions through nonbonding electrons of the nitrogen. Particularly, range of transition metal complexes of azomethine ligands derived from the reaction of 3-amino-1-phenyl-2-pyrazoline-5-one, [6][7][8][9] Herein, we report the synthesis schiff base complexes 5-[(2-Hydroxy-naphthalen-1ylmethylene)-amino]-2-phenyl-2,4-dihydro-pyrazol-3-one and characterization by spectrophotometric methods in addition to estimating the biological activity and studying the antioxidants of the prepared compounds.…”