Some physical and chemical characteristics of Sri Lankan nutmeg oil

Sarath-Kumara, Subaddarage J.; Jansz, E.R.; Dharmadasa, H M

doi:10.1002/jsfa.2740360208

Cited by 13 publications

(6 citation statements)

References 5 publications

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“…The specific gravity of the studied essential oil was 0.890,Sarath-kumara [22] have mentioned that the specific gravity of the East Indian Nutmeg oil ranges from 0.885 to 0.915 and that of west Indian has been 0.860 to 0.88 at 20˚ C. Leela [14] has also report that the specific gravity of east Indian oil is ranging from 0.880 to 0.913 and that of west Indian is ranging from 0.859 to 0.865.…”

Section: Resultsmentioning

confidence: 94%

Hepatotoxic Activity of Essential Oil from Nutmeg (Myristica Fragrans) Against Tetrachloride-Induced Hepatic Damage In Mice

Al-Jumaily¹

2012

IOSJPBS

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To extracting and purifying the essential oil containing terpenes from dried seeds of nutmeg Myristica fragrans available in Iraqi markets. Male albino mice (n= 44), with average weight (25-28 g) of about six weeks old The study also employed an in vivo evaluation of the hepatotoxic effect of essential oil in male albino mice at different concentrations (500 and 1000 mg / kg) given orally for 7 days including biochemical functions serum glutamic pyruvic transaminase (SGPT),serum glutamic oxaloacetic transaminase (SGOT) and serum alkaline phosphatase (SALP) as parameters of liver function tests and serum total bilirubin (TSB). At day 8 the animal was sacrificed and the liver is weighed and kept in 10% formalin for preparation of histopathological sections. The serum was isolated from the blood for the biochemical tests. Statistical results showed the absence of any significant changes on body weight and liver weight of nutmeg treated mice. However nutmeg treated mice showed statistically significant alteration in the biochemical indicators of liver function including significant elevation in SAST, SALT, SALP and TSB in a dose dependent manner. The nutmeg essential oil carries a marked specific potential toxicity to the liver parenchyma, this is very important to be considered for further experimental and clinical studies.

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Section: Resultsmentioning

confidence: 94%

Hepatotoxic Activity of Essential Oil from Nutmeg (Myristica Fragrans) Against Tetrachloride-Induced Hepatic Damage In Mice

Al-Jumaily¹

2012

IOSJPBS

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“…Also the value is in the range of refractive index of East Indian nutmeg oil mentioned by Sarath-kumara et al [30].…”

Section: Sensory Evaluation For the Essential Oilmentioning

confidence: 69%

“…Sarath-kumara et al [28] have mentioned that the specific gravity of the East Indian Nutmeg oil ranges from 0.885 to 0.915 and that of west Indian has been 0.860 to 0.88 at 20˚C, Leela [7] has also report that the specific gravity of east Indian oil is ranging from 0.880 to 0.913 and that of west Indian is ranging from 0.859 to 0.865. Reineccius [29] have reported that the specific gravity of east Indian has been 0.880 -0.910 and of west Indian has been 0.854-0.880 at 25˚C.…”

Section: Sensory Evaluation For the Essential Oilmentioning

confidence: 98%

Extraction and Purification of Terpenes from Nutmeg (myristica fragrans)

Al-Jumaily

Al-Amiry

2012

JNUS

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This study was conducted with the aim to extract and purify the essential oil containing terpenes from the dried seeds of nutmeg myristica fragrans available in Iraqi markets.The essential oil was extracted by steam distillation method with a yield of 4.7 -7.5 gm / 100 gm, and the resultant oil was subjected to sensory and physical evaluation. It has a special spicy odor, slightly pungent taste, colorless to pale yellow in color, not dissolved in water but dissolved in organic solvents like ethanol, hexane, chloroform and ether. The specific gravity, refractive index and optical rotation were (0.890 gm / ml), (1.4822) and (+22˚), respectively. Gas chromatography is used for the quality and quantity evaluation of the essential oil constituents which revealed the presence of 49 volatile compounds. The methanolic extract obtained by reflux the seeds powder with 70% methanol in soxhlet apparatus and yield 12.8%. The extract was subjected to phytochemical detection which confirms the presense of alkaloids, terpenes, flavonoids, glycosides, tannins and resins, with the exception of saponins and coumarines which gave negative tests. Myristicin was purified from the methanolic extract of nutmeg dried seeds, which were detected in the essential oil by TLC and vanillin-H2SO4 reagent. The purified myristicin was obtained after the application of adsorption chromatography on silica gel column and detected on T.L.C. plate with standard myristicin.Both the essential oil and purified myristicin were subjected to gas chromatography which showed the presence of myristicin in the oil in a concentration of 6%.

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“…Compositional data are presented from Baldry et al (1976) on East and West Indian oil, and Sarath-Kumara, Jansz and Dharmadasa (1985) on Sri Lankan oil (Table 7-59).…”

Section: Oil Of Nutmegmentioning

confidence: 97%

Natural Flavoring Materials

Reineccius

1995

Source Book of Flavors

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Some physical and chemical characteristics of Sri Lankan nutmeg oil

Cited by 13 publications

References 5 publications

Hepatotoxic Activity of Essential Oil from Nutmeg (Myristica Fragrans) Against Tetrachloride-Induced Hepatic Damage In Mice

Hepatotoxic Activity of Essential Oil from Nutmeg (Myristica Fragrans) Against Tetrachloride-Induced Hepatic Damage In Mice

Extraction and Purification of Terpenes from Nutmeg (myristica fragrans)

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