Some Reactions of Rabbit Spermatozoa to Ligation of the Epididymis

Gaddum, Penelope; Glover, T. D.

doi:10.1530/jrf.0.0090119

Cited by 46 publications

(19 citation statements)

References 12 publications

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“…He also noticed prominent vivid cream coloured convulsions of the tubule and patches of cream coloured area both on the body and head of the epididymis. Histologically the epididymal tubules showed distension, with flattening and loss of cilia of the lining epithelium.The testis showed the distension of the seminiferous tubules and spermatogenesis remained unchanged till 21 days.In authors series the epididymal changes were similar to those observed by Glover 4 but spermatogenesis was effected in the middle of 2 nd week with varying degrees of shedding of seminiferous epithelium into the lumen.Gaddum and Glover 3 and Reddys 8 observations were in complete agreement with those of authors observations after ligation of the body of the epididymis. The author observed over distension of the epididymis ,proximal to the ligation ,development of discrete cream coloured patches, where the tubule was excessively distended and conspicuous convulsions of the ductus epididymis on the body and head of the epididymis.These observations were similar to those observed by above mentioned investigators Paufler and Foote 7 in their series of experiments noticed severe effects following the ligation of the middle of the epididymis.…”

Section: Ligation Of Body Of Epididymissupporting

confidence: 88%

Macroscopic and Microscopic Study of the Testis after Ligation Of Head And Body Of Epididymis In Adult Male Albino Rats.

Murudkar¹

2013

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Section: Ligation Of Body Of Epididymissupporting

confidence: 88%

Macroscopic and Microscopic Study of the Testis after Ligation Of Head And Body Of Epididymis In Adult Male Albino Rats.

Murudkar¹

2013

iosrphr

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“…This is shown most clearly after vasectomy when the vas deferens and cauda epididymidis become so engorged with spermatozoa that after 6 months they are larger than the testis (Jones, 1974;Bedford, 1976). Other investigators have also performed ligation experiments on the rabbit epididymis but none has reported granulomata (Gaddum & Glover, 1965;Paufler & Foote, 1969). In our experience they are a rare occurrence and can usually be attributed to poor surgical technique.…”

Section: Discussionmentioning

confidence: 59%

Changes in luminal plasma and disappearance of spermatozoa from the ligated cauda epididymidis of the androgen-deficient rabbit

Jones¹,

Dott²

1980

Reproduction

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By 3 weeks after castration the majority of spermatozoa in the ligated cauda epididymidis were dead and decapitated and there was a 46% reduction in the total number of spermatozoa. By 5 weeks after castration > 99% of spermatozoa had disappeared. Electrophoresis of cauda epididymal plasma (CEP) on polyacrylamide gels revealed that after castration the protein composition of CEP changed from a pattern specific to the epididymis to one similar to blood serum. These changes in the luminal content could be prevented by administering testosterone. When spermatoza from the cauda epididymidis were diluted in CEP from normal rabbits they remained motile for several hours at room temperature. Dilution in CEP from 3- ro 5-week castrated animals stimulated vigorous forward motility but this declined to very low levels after 40 min. The evidence indicates that dead spermatozoa can be removed from the epididymis after castration by mechanisms not involving granuloma formation.

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“…Liga¬ tion experiments in rabbits have shown, however, that spermatozoa contained in the head of the epididymis do show certain changes that are usually associated with maturation, e.g. increased capacity for in-vitro motility (Gaddum «fe Glover, 1964).…”

Section: Discussionmentioning

confidence: 99%

DISTRIBUTION OF 5α-Dihydrotestosterone IN THE EPIDIDYMIS OF BULL AND BOAR, AND ITS CONCENTRATION IN RAT EPIDIDYMIS AFTER LIGATION OF EFFERENT TESTICULAR DUCTS, CASTRATION AND UNILATERAL GONADECTOMY

Aafjes¹,

Vreeburg²

1972

Journal of Endocrinology

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5\g=a\-Dihydrotestosterone concentrations were appreciably higher than testosterone concentrations in the epididymides of both a bull and a boar. The highest concentration of 5\g=a\-dihydrotestosterone was found in the heads of these organs. When tritiated testosterone was injected into a castrated rat most of the radioactivity recovered from the epididymis was present as 5\ g=a\ \ x=r eq-\ dihydrotestosterone. Recrystallization confirmed the identity of this compound. In a separate experiment the concentration of 5\g=a\-dihydrotestosterone in the epididymis after castration decreased to unmeasurable amounts in about 27 h. This was not the case when only one testis was removed or when testosterone was injected after castration. Ligation of the efferent ducts of a testis on one side resulted in a lowered 5\g=a\-dihydrotestosteron concentration in the epididymis of that side. This finding suggests a possible role of spermatozoa in the metabolism of testosterone to 5\g=a\-dihydrotestosterone. However, the presence of 5\g=a\-dihydrotestosterone in the epididymis of very young rats without spermatozoa showed that spermatozoa are not required for this metabolism.

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Some Reactions of Rabbit Spermatozoa to Ligation of the Epididymis

Cited by 46 publications

References 12 publications

Macroscopic and Microscopic Study of the Testis after Ligation Of Head And Body Of Epididymis In Adult Male Albino Rats.

Macroscopic and Microscopic Study of the Testis after Ligation Of Head And Body Of Epididymis In Adult Male Albino Rats.

Changes in luminal plasma and disappearance of spermatozoa from the ligated cauda epididymidis of the androgen-deficient rabbit

DISTRIBUTION OF 5α-Dihydrotestosterone IN THE EPIDIDYMIS OF BULL AND BOAR, AND ITS CONCENTRATION IN RAT EPIDIDYMIS AFTER LIGATION OF EFFERENT TESTICULAR DUCTS, CASTRATION AND UNILATERAL GONADECTOMY

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