Some See Rising Risks From Too Much Vitamin A

Lomangino, Kevin

doi:10.1097/01.nmd.0000350729.32003.78

Cited by 1 publication

(2 citation statements)

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“…It is unlikely that infants and children in the United States are suffering from subclinical vitamin A toxicity, 19 since young infants and children in the United States have lower levels and stores of vitamin A than adults. [28][29][30] Severe vitamin A deficiency to the degree seen in equatorial countries is not present in the United States.…”

Section: Vitamin a Toxicity And Young Children In The United Statesmentioning

confidence: 99%

“…It is therefore essential that a well-informed and knowledgeable consumer read the label before purchasing any given formulation of cod liver oil. rAtIo oF VItAMIn A to VItAMIn D In the responses to the Commentary from the on-line supplement 17,18 and nutrition newsletter 19 communities, the issue of the proper ratio of vitamin A to vitamin D emerged as a major concern. Whereas the proper ratio is not well established in humans, excellent information is available on this topic for developing poultry, species in which bone growth and calcium metabolism have been closely studied.…”

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Cod Liver Oil, the Ratio of Vitamins A and D, Frequent Respiratory Tract Infections, and Vitamin D Deficiency in Young Children in the United States

Linday

Umhau

Shindledecker

et al. 2010

Ann Otol Rhinol Laryngol

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We would like to take this opportunity to respond to the Commentary by Cannell and his distinguished colleagues 1 (herein referred to as the "Commentary"). We agree that extensive basic research and adult clinical research performed in the past few decades have demonstrated that the levels of vitamin D required for optimal health are much higher than those needed to prevent rickets in children or osteomalacia in adults; it is also clear that vitamin D deficiency and insufficiency, newly defined for optimal health, are widespread. 2 However, as discussed below, we take a different view on several issues criticized by Cannell et al 1 in their Commentary. CoD LIVer oILCod liver oil, available without a prescription for hundreds of years, is a valuable source of vitamins A and D, as well as long-chain omega-3 fatty acids, 3 all of which may be important in the prevention of respiratory tract illnesses in children (see below, Frequent respiratory tract Infections in young Children). In many populations around the world, cod liver oil continues to be a valuable source of these important nutrients. the across-the-board dismissal of cod liver oil as a supplement advocated by the Commentary ignores this reality. Since the advent of synthetic vitamins in the 1950s, cod liver oil has gone out of favor in the United States, and a valuable source of omega-3 fatty acids has thereby been lost. only 2% (2 of 94) of children entering Linday's randomized sites supplementation study had a history of cod liver oil use on study entry. 4

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Section: Vitamin a Toxicity And Young Children In The United Statesmentioning

confidence: 99%

mentioning

confidence: 99%