Sonographic and clinical characteristics of struma ovarii.

Zalel, Yaron; Seidman, Daniel S.; Oren, Mary; Achiron, Reuven; Gotlieb, Walter H.; Mashiach, Shlomo; Goldenberg, Mordechai

doi:10.7863/jum.2000.19.12.857

Cited by 50 publications

(27 citation statements)

References 15 publications

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“…The mean age at diagnosis is 45 years. Patients are often asymptomatic with struma ovarii being an incidental finding on ultrasonography (US) or may present with lower abdominal pain, palpable lower abdominal mass, or abnormal vaginal bleeding (44,46). Malignant transformation is relatively uncommon, reported in about 15% of patients (44).…”

Section: Other Sitesmentioning

confidence: 99%

Ectopic thyroid tissue: anatomical, clinical, and surgical implications of a rare entity

Noussios

Anagnostis²,

Goulis³

et al. 2011

European Journal of Endocrinology

325

429

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Ectopic thyroid tissue is a rare entity resulting from developmental defects at early stages of thyroid gland embryogenesis, during its passage from the floor of the primitive foregut to its final pre-tracheal position. It is frequently found around the course of the thyroglossal duct or laterally in the neck, as well as in distant places such as the mediastinum and the subdiaphragmatic organs. Although most cases are asymptomatic, symptoms related to tumor size and its relationship with surrounding tissues may also appear. Any disease affecting the thyroid gland may also involve the ectopic thyroid, including malignancy. The clinician must distinguish between ectopic thyroid and metastatic deposits emerging from an orthotopic gland, as well as other benign or malignant masses. Thyroid scintigraphy plays the most important role in diagnosing ectopy, but ultrasonography contributes as well. In cases of symptomatic disease, surgery is the treatment of choice, followed by radioiodine ablation and levothyroxine suppression therapy in more refractory cases. This review provides current understanding about the wide clinical spectrum of this rare condition, also referring to optimal diagnostic approach, differential diagnosis, and management strategies.

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Section: Other Sitesmentioning

confidence: 99%

Ectopic thyroid tissue: anatomical, clinical, and surgical implications of a rare entity

Noussios

Anagnostis²,

Goulis³

et al. 2011

European Journal of Endocrinology

325

429

View full text Add to dashboard Cite

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“…To our knowledge, this is the second report on testosteroneproducing benign Leydig cells from a mature teratoma, 3 and we are unaware of another case in a premenopausal patient. Second, we report the presence of blood flow within a mature ovarian teratoma 4 that was not related to thyroid tissue or malignant transformations. 5 A mature cystic teratoma is a tumor that is capable of differentiating to different cell lines and producing a variety of tissues.…”

Section: Discussionmentioning

confidence: 88%

Testosterone‐Secreting Mature Ovarian Teratoma Causing Severe Virilization in an Adolescent

Rotenberg

Shahabi

Dar

2009

J of Ultrasound Medicine

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A 15-year-old nulligravida came to our clinic with hirsutism, acne, voice changes, menometrorrhagia, clitoromegaly, and an abdominal mass. She had her menarche at 12 years of age and, since then, had had regular periods. She was never sexually active. Two years earlier, she was hospitalized for several months with seizures and a mental status change that was diagnosed as Mycoplasma encephalitis. A few months after her discharge, hirsutism and aggressive behavioral changes developed, which were attributed to her encephalitis. This was followed by development of an adult masculine voice and irregular periods. Her vocal cords were visualized and were found to be normal. The patient was referred to our clinic after she was noted to have increased abdominal girth, and a large cystic mass was palpated in the left adnexa. Case ReportSonographic and Color Doppler Characteristics yperandrogenism, associated with hirsutism in adolescent girls and premenopausal women, is a common cause of irregular menses; it affects 5% to 7% of adult women.1 The most common etiology of androgen disorders is polycystic ovary syndrome, occurring in 70% to 80% of cases. 1,2Androgen-secreting neoplasms are rare and account for less than 0.3% of patients with hirsutism.2 These neoplasms should be suspected when the onset of androgenic symptoms is rapid and sudden. We report a rare case of an adolescent girl with severe virilism and behavioral changes associated with a testosterone-secreting mature ovarian teratoma.H

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“…The ultrasound features of struma ovarii are also nonspecific, predominantly solid mass may be seen and also difficult to distinguish between struma ovarii and dermoid cysts on the basis of their sonographic appearance. 4 Only preoperative scintigraphy with radioactive iodine (I 131) of pelvis could show active thyroid tissue. 5 Diagnosis confirmed by histopathological examination, which typically consists of normal-appearing thyroidal tissue composed of thyroid follicles of various sizes.…”

Section: Discussionmentioning

confidence: 99%