Sonographic and mammographic appearances of granular cell tumors of the breast with pathological correlation

Yang, Wei Tse; Edeiken-Monroe, Beth S; Sneige, Nour; Fornage, Bruno D.

doi:10.1002/jcu.20227

Cited by 53 publications

(43 citation statements)

References 11 publications

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“…Microcalcifications are not normally a feature of GCTs. On ultrasound, GCTs can present as solid, poorly marginated lesions with marked posterior shadowing or as more benign-appearing well-circumscribed solid masses (8,9). MRI findings in a patient with GCT were described by Scaranelo et al (10).…”

Section: Discussionmentioning

confidence: 94%

Granular cell tumor in axillary region: A rare entity

2018

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Abstract. A granular cell tumor (GCT), is a rare soft tissue tumor which may occur throughout the body, usually in the head and neck, skin or subcutaneous tissues of the trunk and upper extremities, and female genital region. A total of 5-8% of all cases of GCTs occur in the breast. GCT of the breast may mimic breast cancer both clinically and radiologically. GCTs are usually benign and solitary; however, approximately 2% occur as malignant tumors. Benign GCTs are treated with wide local excision and are associated with a good prognosis. The current case report presents findings in a patient with a benign form of GCT in a rare location, specifically in the axillary region.

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Section: Discussionmentioning

confidence: 94%

Granular cell tumor in axillary region: A rare entity

2018

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“…Mammography usually reveals a stellate, speculated mass, without calcifications, but can also show a round, well-circumscribed mass. Ultrasound usually shows a solid, poorly marginated mass with posterior shadowing, even if a more benign-appearing mass can be seen [9]. Not even magnetic resonance imaging (MRI) has shown specific patterns allowing differentiating GCTB from cancer.…”

Section: Discussionmentioning

confidence: 98%

Granular cell tumor of the male breast

Taglietti¹,

Vettoretto²,

Blanzuoli³

et al. 2011

Updates Surg

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A 54-year-old male presented with a painless, hard, irregular lump in his right breast, with fixation to the pectoralis muscle. Mammography and ultrasound showed a 2.5-cm mass suspicious of malignancy. The patient underwent a wide local excision. A 2.5-cm hard, stellate lump was found and sent to the pathologist, which revealed this to be a benign granular cell tumor. Granular cell tumor of the breast is a rare neoplasm, of unknown etiology, which is benign in 98% of cases, but mimics breast cancer, causing challenging diagnostic and therapeutic dilemmas. Traditional imaging techniques do not recognize any feature specific for this tumor. Only excisional biopsy allows the detection of the distinct histological and immunohistochemical profile of the lesion (granular cytoplasm and staining for the S-100 protein). Only local surgical excision is indicated. General and senologist surgeons must be aware of this entity to avoid unnecessary mastectomy or lymphadenectomy.

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“…At ultrasound, GCT may manifest as a solid, poorly marginated mass with marked posterior acoustic shadowing (4), alternatively it may have a benign appearance as a well-circumscribed solid mass (5,6).…”

Section: Discussionmentioning

confidence: 99%

A rare tumor mimicking breast carcinoma

Celebi

Toksoy

Özel

et al. 2012

Journal of the Belgian Society of Radiology

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Granular cell tumor is a rare benign soft-tissue neoplasm, usually appearing in the tongue, the oral cavity and subcutaneous tissue. Examples of granular cell tumor of breast are encountered in 30-50-year-old women. Herein, we report ultrasonographic and mammographic imaging findings of a 59 years old woman presented with a painless palpable mass, which was diagnosed as granular cell tumor on histopathological analysis. Key-word: Breast neoplasms.

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Sonographic and mammographic appearances of granular cell tumors of the breast with pathological correlation

Abstract: Breast imagers should be aware that GCT of the breast is an uncommon differential in a minority of neoplasms that can be mistaken for breast cancer.

Cited by 53 publications

References 11 publications

Granular cell tumor in axillary region: A rare entity

Granular cell tumor in axillary region: A rare entity

Granular cell tumor of the male breast

A rare tumor mimicking breast carcinoma

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