Sonographic assessment of calcium pyrophosphate deposition disease at wrist. A focus on the dorsal scapho-lunate ligament

Cipolletta, Edoardo; Smerilli, Gianluca; Mirza, Riccardo Mashadi; Matteo, Andrea Di; Carotti, Marina; Salaffi, Fausto; Grassi, Walter; Filippucci, Emilio

doi:10.1016/j.jbspin.2020.04.012

Cited by 10 publications

(21 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our study confirms that US examination of SLIL may add useful information in cases of suspected CPDD. Even if our data cannot confirm that CPPD crystals could be directly associated to SLIL degeneration, the US detection of hyperechoic foci suggestive for CPPD crystals confirms its high diagnostic accuracy in the diagnosis of CPDD (7,26) .…”

Section: Discussionmentioning

confidence: 73%

“…Ultrasound evaluation of the scapholunate ligament and scapholunate joint space in patients with wrist complaints in a rheumatologic setting Secondly, no comparison of US measurements and findings with the imaging gold standards such as radiography or MRI was made, since the study was carried out in a scenario of real clinical practice, where only a minority of patients need to undergo other imaging techniques. However, all US measurements were standardized and repeatable on the basis of previous studies (7,14,19,20) . Thirdly, the small number of subjects and nonhomogeneity of the cohort in terms of age and disease duration do not allow to draw definitive conclusions about the causative factors of SLIL degeneration.…”

Section: Discussionmentioning

confidence: 99%

“…A dichotomous score for the presence/absence of hyperechoic deposits (at least two distinct spots) in the ligament and osteophytosis of the scapholunate joint was adopted. Ultrasound evaluation of the scapholunate ligament and scapholunate joint space in patients with wrist complaints in a rheumatologic setting CPPD crystal deposits were assessed and defined according to the Outcome Measure in Rheumatology (OMERACT) definitions (7,19,20) .…”

Section: Methodsmentioning

confidence: 99%

“…The proximal cause of osteoarthritis involving the wrist (5) . Both calcium pyrophosphate dihydrates (CPPD) crystal deposition disease (CPDD) arthropathy and rheumatoid arthritis (RA) are rheumatologic conditions associated with wrist instability and SLAC (6)(7)(8)(9) .…”

Section: Introductionmentioning

confidence: 99%

“…3. Dorsal axial scan on a rheumatoid wrist(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18). Severe degeneration of scapholunate interosseous ligament (absence of definite ligamentous structure), with dissociation >3.5 mm between scaphoid (S) and lunate (L) bones, consistent with scapholunate advanced collapse (SLAC).…”

mentioning

confidence: 99%

See 4 more Smart Citations

Ultrasound evaluation of the scapholunate ligament and scapholunate joint space in patients with wrist complaints in a rheumatologic setting

et al. 2021

View full text Add to dashboard Cite

Aim: The aims of the study were to perform an ultrasound assessment of the dorsal portion of the scapholunate interosseous ligament and scapholunate joint space in patients with wrist complaints in a rheumatologic setting, to describe ultrasound abnormalities about scapholunate interosseous ligament region, and to correlate them with clinical data, presence of dorsal ganglion cysts and diagnoses of rheumatic diseases. Material and methods: Seventy-four consecutive patients with wrist pain and/or swelling were evaluated by routine power Doppler ultrasound. Forty normal wrists were studied to confirm the normality values of the scapholunate joint. Results: The mean width of the normal scapholunate joint was 2.49 mm (±0.49 SD), with a coefficient of variation on repeated measurements of 3.662%. The best predictors of scapholunate interosseous ligament degeneration were: older age (p <0.0001), male gender (p = 0.0049), and radiocarpal effusion (p = 0.0156). The presence of osteophytosis and calcifications of the scapholunate joint were higher (p <0.001) in rheumatic patients. Scapholunate calcifications showed a sensitivity of 98.2% and a specificity of 61.1% for calcium pyrophosphate deposition disease. Dorsal ganglion cysts were more frequent in younger subjects (p <0.0012) without rheumatic conditions (p <0.0001) or midcarpal synovitis (p <0.0001). Larger cysts often exhibited power Doppler signal (p <0.0001). The best predictors of scapholunate dissociation were: male gender (p = 0.0002), presence of midcarpal synovitis (p <0.0137), and higher grade of scapholunate interosseous ligament degeneration (p <0.0001). Scapholunate widening was greater (p = 0.0419) in calcium pyrophosphate deposition disease or rheumatoid arthritis than in other rheumatic conditions. Conclusions: Ultrasound findings of scapholunate interosseous ligament degeneration and calcification, scapholunate space enlargement, and dorsal ganglion cysts should be considered in ultrasound reporting, since they add useful information about the diagnosis of associated rheumatic conditions.

show abstract

Section: Discussionmentioning

confidence: 73%