Sonographic detection of bilateral striopallidodentate calcinosis

Krogias, Christos; Meves, Saskia H.; Schoellhammer, Martin; Gold, Ralf; Andrich, Juergen

doi:10.1007/s00415-009-0889-z

Cited by 7 publications

(6 citation statements)

References 6 publications

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“…TCS can be useful in assessing secondary Parkinsonisms by detecting enlargement of the ventricular system in patients with hydrocephlus,45, 46 trace metal accumulation in Wilson's disease71 or manganism,72 calcification in the basal ganglia,73 and vascular parkinsonism, as determined by changes on Doppler or duplex sonography in conjunction with normal SN echogenicity 55, 74. SN echogenicity is usually normal in patients with unipolar depression75–77 and essential tremor57, 78, 79 and can be readily distinguished from idiopathic PD.…”

Section: Transcranial Sonographymentioning

confidence: 99%

Milestones in magnetic resonance imaging and transcranial sonography of movement disorders

et al. 2011

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Twenty-five years ago, when this journal was initiated, imaging of movement disorders was in its infancy. Since that time, magnetic resonance imaging has become a standard technique that is routinely performed in patients with movement disorders in order to exclude secondary causes and in some instances to provide specific information that aids in making the diagnosis of a neurodegenerative condition. Transcranial sonography is a more recent advance and is now widely employed to aid in the diagnosis of Parkinson's disease and possibly in detecting individuals in the premotor phases of the disease. Investigations are currently under way to evaluate the value of this technique in other movement disorders.

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Section: Transcranial Sonographymentioning

confidence: 99%

Milestones in magnetic resonance imaging and transcranial sonography of movement disorders

et al. 2011

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“…We report a case of IBGC presenting with L ‐dopa‐responsive parkinsonism, progressive cognitive impairment, frontal lobe dysfunction, limb ataxia, and mild leg spasticity as well as provide TCS results which demonstrate extensive intracranial calcifications 9, 10. Basal ganglia, but not periventricular hyperechogenicity, has been found repeatedly in atypical parkinsonism, especially in progressive supranuclear palsy and multiple system atrophy (MSA‐P) 3.…”

Section: Discussionmentioning

confidence: 99%

“…The most important reason for increased basal ganglia hyperechogenicity are, however, circumscribed calcifications, which can be found in 5 to 10% of neurologically healthy subjects. Markedly increased areas of basal ganglia hyperechogenicity due to extensive calcifications were recently described in patients with bilateral striopallidodentate calcinosis, also referred to as (idiopathic) basal ganglia calcification 9, 10. Small intracranial calcifications can occasionally be detected on TCS before they become evident on computer tomography (CT) or magnetic resonance (MR) imaging, respectively 7, 11.…”

mentioning

confidence: 99%

Distinct basal ganglia hyperechogenicity in idiopathic basal ganglia calcification

et al. 2010

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We report a 67-year-old patient with idiopathic basal ganglia calcification (IBGC). He presented with progressive cognitive impairment, frontal lobe dysfunction, mild leg spasticity, and levodopa (L-dopa)-responsive parkinsonism. Transcranial sonography (TCS) revealed marked hyperechogenicity of the basal ganglia and periventricular spaces bilaterally. The detected signal alterations showed a fairly symmetric distribution and corresponded to the hyperintense calcifications depicted on the computer tomography brain scan. The combination of symmetric hyperechogenic areas adjacent to the lateral ventricles and of the basal ganglia may serve as an imaging marker characteristic of IBGC. Hyperechogenicity due to extended basal ganglia calcification as presented here is distinct from the pattern of hyperechogenicity caused by heavy metal accumulation, which is described to be less striking. In addition to atypical parkinsonian syndromes such as progressive supranuclear palsy and multiple system atrophy, IBGC is thus another differential diagnosis of parkinsonism with basal ganglia hyperechogenicity.

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“…In idiopathic basal ganglia calcification (IBGC) symmetric hyperechogenic signals are seen corresponding to the calcifications detected by computer tomography [38,39].…”

Section: Differential Diagnosis: Pd Vs Secondary Parkinsonismmentioning

confidence: 98%

Developments in the Role of Transcranial Sonography for the Differential Diagnosis of Parkinsonism

Padovani

Yılmaz

Berg

2015

Curr Neurol Neurosci Rep

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In the last two decades transcranial sonography (TCS) has developed as a valuable, supplementary tool in the diagnosis and differential diagnosis of movement disorders. In this review, we highlight recent evidence supporting TCS as a reliable method in the differential diagnosis of parkinsonism, combining substantia nigra (SN), basal ganglia and ventricular system findings. Moreover, several studies support SN hyperechogenicity as one of most important risk factors for Parkinson's disease (PD). The advantages of TCS include short investigation time, low cost and lack of radiation. Principal limitations are still the dependency on the bone window and operator experience. New automated algorithms may reduce the role of investigator skill in the assessment and interpretation, increasing TCS diagnostic reliability. Based on the convincing evidence available, the EFNS accredited the method of TCS a level A recommendation for supporting the diagnosis of PD and its differential diagnosis from secondary and atypical parkinsonism. An increasing number of training programmes is extending the use of this technique in clinical practice.

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Sonographic detection of bilateral striopallidodentate calcinosis

Cited by 7 publications

References 6 publications

Milestones in magnetic resonance imaging and transcranial sonography of movement disorders

Milestones in magnetic resonance imaging and transcranial sonography of movement disorders

Distinct basal ganglia hyperechogenicity in idiopathic basal ganglia calcification

Developments in the Role of Transcranial Sonography for the Differential Diagnosis of Parkinsonism

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