Sonographic diagnosis of lipoma of the corpus callosum.

Prenatal Ultrasonographic Diagnosis of Fetal Intracranial Tumors: A Review

“…These rare tumors, when large, may be associated with agenesis of the corpus callosum and other dysraphic findings including: meningomyelocele, encephalocele, cranium bifidum, hypertelorism, median clefting, and others, symptomatology includes headaches, seizures, and mental retardation. 57 It appears that approximately 50% of the patients may be asymptomatic, usually in association with smaller size lipomas, in the absence of associated anomalies. In these cases the lipomas usually are located upon the superior surface of the intact corpus callosum, and may only be detected as an incidental finding at autopsy.…”

“…In these cases the lipomas usually are located upon the superior surface of the intact corpus callosum, and may only be detected as an incidental finding at autopsy. 57 Following the report of sonographic diagnosis of lipoma of the corpus callosum in neonates by Sauerbrei and Cooperberg, 58 Christensen et al 57 described an unusual case in which prenatal ultrasonography at 40 weeks' gestation disclosed a small midline hyperechoic intracranial structure of unknown significance. Neonatal cranial ultrasonography at 24 hr of life confirmed a hyperechoic smoothly marginated zone immediately adjacent to the superior aspect of the corpus callosum, measuring 2.7 X 0.7 cm in size and extending posteriorly from the midportion of the corpus curving around the splenium.…”